The Indiana Alzheimer Disease Center (IADC) is established on the campus of Indiana University School of Medicine. It is comprised of six cores: Administrative Core, Clinical Core, Data Management and Statistics Core, Neuropathology Core, Education and Information Transfer Core and Neuroimaging Core. The mission of the IADC is: 1) to support and carry out research on Alzheimer disease (AD) and other neurodegenerative dementias, 2) to serve as shared research resources that will facilitate research in AD and other dementias, 3)distinguish them from the processes of normal brain aging and mild cognitive impairment (MCI), 4) provide a platform for training, 5) develop novel techniques and methodologies, and 6) translate these research findings into better diagnostic, prevention and treatment strategies. The focus of the IADC is on behavioral neurology, clinicopathological correlations, biochemistry, and genetics of AD, frontotemporal dementia and Parkinsonism linked to chromosome 17 (FTDP-17), Gerstmann-Strussler-Scheinker disease (GSS), Parkinson disease and other hereditary diseases associated with abnormal protein accumulation.
It is estimated that as many as 5 million Americans have AD. The Indiana Alzheimer Disease Center provides an environment and resources directed towards fostering and coordinating research and educational activities on AD and other dementing illnesses.
|Ramanan, V K; Nho, K; Shen, L et al. (2015) FASTKD2 is associated with memory and hippocampal structure in older adults. Mol Psychiatry 20:1197-204|
|Austrom, Mary Guerriero; Geros, Kristin N; Hemmerlein, Kimberly et al. (2015) Use of a multiparty web based videoconference support group for family caregivers: Innovative practice. Dementia (London) 14:682-90|
|De, Wang; Wang, Yang; Nie, Feiping et al. (2014) Human connectome module pattern detection using a new multi-graph MinMax cut model. Med Image Comput Comput Assist Interv 17:313-20|
|Ramanan, V K; Risacher, S L; Nho, K et al. (2014) APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study. Mol Psychiatry 19:351-7|
|Yan, Jingwen; Du, Lei; Kim, Sungeun et al. (2014) Transcriptome-guided amyloid imaging genetic analysis via a novel structured sparse learning algorithm. Bioinformatics 30:i564-71|
|Boespflug, Erin L; Storrs, Judd; Sadat-Hossieny, Sara et al. (2014) Full diffusion characterization implicates regionally disparate neuropathology in mild cognitive impairment. Brain Struct Funct 219:367-79|
|Cheng, Yibin; Jin, Yinlong; Unverzagt, Frederick W et al. (2014) The relationship between cholesterol and cognitive function is homocysteine-dependent. Clin Interv Aging 9:1823-9|
|Oblak, Adrian L; Hagen, Matthew C; Sweadner, Kathleen J et al. (2014) Rapid-onset dystonia-parkinsonism associated with the I758S mutation of the ATP1A3 gene: a neuropathologic and neuroanatomical study of four siblings. Acta Neuropathol 128:81-98|
|Nuytemans, Karen; Inchausti, Vanessa; Beecham, Gary W et al. (2014) Absence of C9ORF72 expanded or intermediate repeats in autopsy-confirmed Parkinson's disease. Mov Disord 29:827-30|
|Jessen, Frank; Amariglio, Rebecca E; van Boxtel, Martin et al. (2014) A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease. Alzheimers Dement 10:844-52|
Showing the most recent 10 out of 255 publications