The Education an Information Transfer Core (EITC) is dedicated to the continued support and promotion of the ADC Center and activities. We propose three Specific Aims: to continue developing timely resources and information for patients, care providers and communities;to support investigator research at UTSW through patient recruitment and retention and physician education;and, to advance the goals of the ADC by collaborating with the University, state and national programs, and the network of ADC Centers and affiliates. 1. Creation and Maintenance of Education Core Resources: The EITC will develop and maintain Core resources through participating in activities and events that publicize the ADC Center, and by providing printed and/or web-based information for ADC participants, their families, and for the communities that we serve. 2. Support investigator-initiated research at UTSW and affiliated institutions through recruitment, retention and education: The EITC will help recruit and retain subjects for research protocols and clinical trials of the ADC Clinical Core. EITC materials will continue to focus on the importance of early disease detection and treatment, and vascular risk factors for AD, particularly in Dallas'African American and Hispanic communities. Focus groups and/or community advisory committees will be formed to assist in our planning. Education programs for medical students will be implemented. 3. Support state-wide and national efforts related to normal aging, Alzheimer's disease and other dementias research: Since important research on AD and related disorders requires large cohorts that can only be obtained through large collaborative efforts, this aim of the EITC includes supportive training programs and/or symposiums for physicians and healthcare professionals in collaboration with other ADCs and local/state and national organizations.

Public Health Relevance

The development of successful therapies for Alzheimer's disease (AD) will require a thorough understanding of the pathologic mechanisms that contribute to neurodegeneration. Data from epidemiologic and observational studies indicates that vascular and inflammatory pathology contributes to AD. The goal of the UTSW ADC is to identify biomarkers of vascular and inflammatory pathology that will be useful for selection of participants in clinical trials.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
5P30AG012300-18
Application #
8382578
Study Section
Special Emphasis Panel (ZAG1-ZIJ-5)
Project Start
Project End
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
18
Fiscal Year
2012
Total Cost
$169,099
Indirect Cost
$72,650
Name
University of Texas Sw Medical Center Dallas
Department
Type
DUNS #
800771545
City
Dallas
State
TX
Country
United States
Zip Code
75390
Schaffert, Jeff; LoBue, Christian; White, Charles L et al. (2018) Traumatic brain injury history is associated with an earlier age of dementia onset in autopsy-confirmed Alzheimer's disease. Neuropsychology 32:410-416
Rosenberg, Roger N; Fu, Min; Lambracht-Washington, Doris (2018) Intradermal active full-length DNA A?42 immunization via electroporation leads to high anti-A? antibody levels in wild-type mice. J Neuroimmunol 322:15-25
Davis, Jeremy J (2018) Performance validity in older adults: Observed versus predicted false positive rates in relation to number of tests administered. J Clin Exp Neuropsychol 40:1013-1021
Lin, Ming; Gong, Pinghua; Yang, Tao et al. (2018) Big Data Analytical Approaches to the NACC Dataset: Aiding Preclinical Trial Enrichment. Alzheimer Dis Assoc Disord 32:18-27
Kirson, Noam Y; Scott Andrews, J; Desai, Urvi et al. (2018) Patient Characteristics and Outcomes Associated with Receiving an Earlier Versus Later Diagnosis of Probable Alzheimer's Disease. J Alzheimers Dis 61:295-307
Pottier, Cyril; Zhou, Xiaolai; Perkerson 3rd, Ralph B et al. (2018) Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. Lancet Neurol 17:548-558
Crum, Jana; Wilson, Jeffrey; Sabbagh, Marwan (2018) Does taking statins affect the pathological burden in autopsy-confirmed Alzheimer's dementia? Alzheimers Res Ther 10:104
Burke, Shanna L; Cadet, Tamara; Maddux, Marlaina (2018) Chronic Health Illnesses as Predictors of Mild Cognitive Impairment Among African American Older Adults. J Natl Med Assoc 110:314-325
Weintraub, Sandra; Besser, Lilah; Dodge, Hiroko H et al. (2018) Version 3 of the Alzheimer Disease Centers' Neuropsychological Test Battery in the Uniform Data Set (UDS). Alzheimer Dis Assoc Disord 32:10-17
Kamara, Dennis M; Gangishetti, Umesh; Gearing, Marla et al. (2018) Cerebral Amyloid Angiopathy: Similarity in African-Americans and Caucasians with Alzheimer's Disease. J Alzheimers Dis 62:1815-1826

Showing the most recent 10 out of 385 publications