The Population Aging Research Center (PARC) at the University of Pennsylvania proposes a 5-year continuation of its existing P30 Center, with the following five signatures themes for 2014-2019: i) Health, disease, and mortality risks at older ages, incorporating race and gender differences, including period and cohort risks and their underlying social and biological mechanisms;ii) Early-life conditions and older adult health, behavior, and well-being: an exploration of early developmental circumstances that may be crucial for shaping how we grow old, including nutrition, infectious disease, social support, education, and gene-environment interactions prenatally and during childhood;iii) Global aging: sociocultural, economic, and environmental circumstances impacting the well-being of older individuals around the world;consequences for health and aging of lifestyle changes on rapidly transitioning developing countries;iv) Biodemographical and evolutionary approaches to life history, including innovative analytic methodologies for collecting and analyzing metabolic, and genetic biomarkers of aging, evaluation of non-human animal models for explaining human aging trajectories, and use of evolutionary frameworks for re-interpreting data and generating new testable hypotheses;v) Domestic/international perspectives on well-being at older ages, emphasizing lifecycle decision-making and old-age financial security and their interactions with changing work patterns, family support, savings and pensions, health insurance, and health care systems. Attentive to the current budgetary situation, PARC has restructured and streamlined its operations to propose a smaller, but highly efficient and productive Center that is the hub of research activity of 35 Research Associates working on aging-related issues. Three Cores are proposed: Core A: "Administrative & Research Support"(Valeggia, PI) to provide dedicated administrative and data management services to Associates, convene an External Advisory Committee, and establish an initiative aimed at increasing the number of NIH/NIA grant applications, especially from Pilot projects Pi's;Core B: "Program Development" (Valeggia, PI) to sustain &evaluate the Pilot Program;support is requested for three 2-year pilots that emphasize one or more signature themes;Core C: "External Innovative Network" (Behrman, PI) to expand and strengthen five research &collaboration networks: the Latin American Network on Aging (LANA), the Network on Aging in Sub-Saharan Africa (NASSA), the Evolutionary Network (EvoDemo), the Network on Effects of Early Life on Mature Adults (NEELMA), and the Network on Migration Advantage (NeMA).

Public Health Relevance

PARC shapes public health policy in several ways: Through its Pilot Program, our research associates evaluate new hypotheses, focusing on health and well-being at older ages as an outcome of the life-long interaction of health and wealth over the entire life cycle. Innovative research on the genetic variation and evolutionary processes associated with chronic diseases. We also focus on the health trajectories of mature adults in different locations around the world, including migration effects.

National Institute of Health (NIH)
Center Core Grants (P30)
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Special Emphasis Panel (ZAG1)
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Patmios, Georgeanne E
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University of Pennsylvania
Schools of Arts and Sciences
United States
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Peltzer, Karl; Szrek, Helena; Ramlagan, Shandir et al. (2015) Depression and social functioning among HIV-infected and uninfected persons in South Africa. AIDS Care 27:41-6
Olmedo, Sofia Irene; Valeggia, Claudia (2014) The initiation of complementary feeding among Qom indigenous people. Arch Argent Pediatr 112:254-7
Jedrziewski, M Kathryn; Ewbank, Douglas C; Wang, Haidong et al. (2014) The Impact of Exercise, Cognitive Activities, and Socialization on Cognitive Function: Results From the National Long-Term Care Survey. Am J Alzheimers Dis Other Demen 29:372-378
Elo, Irma T; Martikainen, Pekka; Myrskylä, Mikko (2014) Socioeconomic status across the life course and all-cause and cause-specific mortality in Finland. Soc Sci Med 119:198-206
Tencza, Christopher; Stokes, Andrew; Preston, Samuel (2014) Factors responsible for mortality variation in the United States: A latent variable analysis. Demogr Res 21:27-70
Helleringer, Stéphane; Mkandawire, James; Kohler, Hans-Peter (2014) A new approach to measuring partnership concurrency and its association with HIV risk in couples. AIDS Behav 18:2291-301
Bove, R M; Vala-Haynes, Emily; Valeggia, Claudia (2014) Polygyny and women's health in rural Mali. J Biosoc Sci 46:66-89
Margolis, Rachel (2013) Educational differences in healthy behavior changes and adherence among middle-aged Americans. J Health Soc Behav 54:353-68
Behrman, Jere R; Parker, Susan W (2013) Is health of the aging improved by conditional cash transfer programs? Evidence from Mexico. Demography 50:1363-86
Margolis, Rachel (2013) Health shocks in the family: gender differences in smoking changes. J Aging Health 25:882-903

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