Abstract

The aims of the core are to continue to develop new models, which includes performing the necessary molecular biology and mouse manipulation (including offering training), and to provide resources and expertise in the construction of targeting vectors, including inducibles, etc. They will also perform cryopreservation.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
3P30AG013280-08S1
Application #
6613334
Study Section
Project Start
2002-08-01
Project End
2003-06-30
Budget Start
Budget End
Support Year
8
Fiscal Year
2002
Total Cost
$193,750
Indirect Cost

  Institution

Name
University of Washington
Department
Type
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195

  Publications

Walters, Ryan O; Arias, Esperanza; Diaz, Antonio et al. (2018) Sarcosine Is Uniquely Modulated by Aging and Dietary Restriction in Rodents and Humans. Cell Rep 25:663-676.e6
Kramer, Philip A; Duan, Jicheng; Gaffrey, Matthew J et al. (2018) Fatiguing contractions increase protein S-glutathionylation occupancy in mouse skeletal muscle. Redox Biol 17:367-376
Kaeberlein, Matt (2018) How healthy is the healthspan concept? Geroscience 40:361-364
Crane, Matthew M; Kaeberlein, Matt (2018) The paths of mortality: how understanding the biology of aging can help explain systems behavior of single cells. Curr Opin Syst Biol 8:25-31
Beaupere, Carine; Dinatto, Leticia; Wasko, Brian M et al. (2018) Genetic screen identifies adaptive aneuploidy as a key mediator of ER stress resistance in yeast. Proc Natl Acad Sci U S A 115:9586-9591
Andeen, Nicole K; Yang, Han-Yin; Dai, Dao-Fu et al. (2018) DnaJ Homolog Subfamily B Member 9 Is a Putative Autoantigen in Fibrillary GN. J Am Soc Nephrol 29:231-239
Urfer, Silvan R; Kaeberlein, Tammi L; Mailheau, Susan et al. (2017) Asymptomatic heart valve dysfunction in healthy middle-aged companion dogs and its implications for cardiac aging. Geroscience 39:43-50
Mendenhall, Alexander; Crane, Matthew M; Leiser, Scott et al. (2017) Environmental Canalization of Life Span and Gene Expression in Caenorhabditis elegans. J Gerontol A Biol Sci Med Sci 72:1033-1037
Beaupere, Carine; Wasko, Brian M; Lorusso, Jared et al. (2017) CAN1 Arginine Permease Deficiency Extends Yeast Replicative Lifespan via Translational Activation of Stress Response Genes. Cell Rep 18:1884-1892
Urfer, Silvan R; Kaeberlein, Tammi L; Mailheau, Susan et al. (2017) A randomized controlled trial to establish effects of short-term rapamycin treatment in 24 middle-aged companion dogs. Geroscience 39:117-127

Showing the most recent 10 out of 168 publications