Clinical research is defined by the National Institutes of Health (NIH) as research conducted with human subjects or using materials of human origin for which an investigator interacts with human subjects.[7] Consistent with the definition used by the NIH and the Institute of Medicine (IOM), we define the term """"""""Clinical Research Enterprise"""""""" as a wide spectrum of research and its applications?from the beginnings of human-oriented bench-top research and its application to patient care, to clinical epidemiology, health services research, outcomes research, and incorporation of these findings into health- and self-care in the community.[8] The major components of the Clinical Research Enterprise include private and public sponsors, research organizations, investigators, participants, oversight entities and stakeholders/consumers. The CLC goal is to create and disseminate evidence-based methods for promoting clinical research in minority communities, to increase community engagement in the clinical research enterprise. Our multi-level strategies will be to: work with communities and researchers to disseminate effective methods for promoting research opportunities, leverage institutional and community infrastructure to support community engagement (participation of community-based organizations, community physicians, patients, and research volunteers) in ail clinical research, and disseminate results of minority aging research to community partners, focusing on San Francisco Bay Area African American, Asian, and Latino populations. Achieving these objectives will result in increased opportunities for minority populations to engage in and benefit from research advances.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Center Core Grants (P30)
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Special Emphasis Panel (ZAG1-ZIJ-3 (M1))
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University of California San Francisco
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Kalkhoran, Sara; Appelle, Nicole A; Napoles, Anna M et al. (2016) Beyond the Ask and Advise: Implementation of a Computer Tablet Intervention to Enhance Provider Adherence to the 5As for Smoking Cessation. J Subst Abuse Treat 60:91-100
Nápoles, Anna María; Appelle, Nicole; Kalkhoran, Sara et al. (2016) Perceptions of clinicians and staff about the use of digital technology in primary care: qualitative interviews prior to implementation of a computer-facilitated 5As intervention. BMC Med Inform Decis Mak 16:44
Mayeda, Elizabeth Rose; Glymour, M Maria; Quesenberry, Charles P et al. (2016) Inequalities in dementia incidence between six racial and ethnic groups over 14 years. Alzheimers Dement 12:216-24
Marden, Jessica R; Mayeda, Elizabeth R; Walter, Stefan et al. (2016) Using an Alzheimer Disease Polygenic Risk Score to Predict Memory Decline in Black and White Americans Over 14 Years of Follow-up. Alzheimer Dis Assoc Disord :
Vivot, Alexandre; Power, Melinda C; Glymour, M Maria et al. (2016) Jump, Hop, or Skip: Modeling Practice Effects in Studies of Determinants of Cognitive Change in Older Adults. Am J Epidemiol 183:302-14
Echeverri, Margarita; Anderson, David; Nápoles, Anna María (2016) Cancer Health Literacy Test-30-Spanish (CHLT-30-DKspa), a New Spanish-Language Version of the Cancer Health Literacy Test (CHLT-30) for Spanish-Speaking Latinos. J Health Commun 21 Suppl 1:69-78
Mejia, Raul; Pérez Stable, Eliseo J; Kaplan, Celia P et al. (2016) Effectiveness of an Intervention to Teach Physicians How to Assist Patients to Quit Smoking in Argentina. Nicotine Tob Res 18:1101-9
Izano, Monika; Wei, Esther K; Tai, Caroline et al. (2016) Chronic inflammation and risk of colorectal and other obesity-related cancers: The health, aging and body composition study. Int J Cancer 138:1118-28
Liu, Rhianon; Chang, Alexandra; Reddy, Sanjay et al. (2016) Improving Patient-Centered Care: A Cross-Sectional Survey of Prior Use and Interest in Complementary and Integrative Health Approaches Among Hospitalized Oncology Patients. J Altern Complement Med 22:160-5
Sternberg, Rosa Maria; Nápoles, Anna Maria; Gregorich, Steven et al. (2016) Development of the Stress of Immigration Survey: A Field Test Among Mexican Immigrant Women. Fam Community Health 39:40-52

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