Clinical research is defined by the National Institutes of Health (NIH) as research conducted with human subjects or using materials of human origin for which an investigator interacts with human subjects.[7] Consistent with the definition used by the NIH and the Institute of Medicine (IOM), we define the term "Clinical Research Enterprise" as a wide spectrum of research and its applications?from the beginnings of human-oriented bench-top research and its application to patient care, to clinical epidemiology, health services research, outcomes research, and incorporation of these findings into health- and self-care in the community.[8] The major components of the Clinical Research Enterprise include private and public sponsors, research organizations, investigators, participants, oversight entities and stakeholders/consumers. The CLC goal is to create and disseminate evidence-based methods for promoting clinical research in minority communities, to increase community engagement in the clinical research enterprise. Our multi-level strategies will be to: work with communities and researchers to disseminate effective methods for promoting research opportunities, leverage institutional and community infrastructure to support community engagement (participation of community-based organizations, community physicians, patients, and research volunteers) in ail clinical research, and disseminate results of minority aging research to community partners, focusing on San Francisco Bay Area African American, Asian, and Latino populations. Achieving these objectives will result in increased opportunities for minority populations to engage in and benefit from research advances.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Center Core Grants (P30)
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Special Emphasis Panel (ZAG1-ZIJ-3)
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University of California San Francisco
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Kwan, Christine Ml; Napoles, Anna M; Chou, Jeyling et al. (2015) Development of a conceptually equivalent Chinese-language translation of the US Household Food Security Survey Module for Chinese immigrants to the USA. Public Health Nutr 18:242-50
Rush, Christina L; Darling, Margaret; Elliott, Maria Gloria et al. (2015) Engaging Latina cancer survivors, their caregivers, and community partners in a randomized controlled trial: Nueva Vida intervention. Qual Life Res 24:1107-18
Kwan, Christine Ml; Napoles, Anna M; Chou, Jeyling et al. (2015) Development of a conceptually equivalent Chinese-language translation of the US Household Food Security Survey Module for Chinese immigrants to the USA - Corrigendum. Public Health Nutr 18:378
Kaplan, Celia P; Livaudais-Toman, Jennifer; Tice, Jeffrey A et al. (2014) A randomized, controlled trial to increase discussion of breast cancer in primary care. Cancer Epidemiol Biomarkers Prev 23:1245-53
Lopez, Monica E; Kaplan, Celia P; Napoles, Anna M et al. (2014) Satisfaction with treatment decision-making and treatment regret among Latinas and non-Latina whites with DCIS. Patient Educ Couns 94:83-9
Afable-Munsuz, Aimee; Mayeda, Elizabeth Rose; Pérez-Stable, Eliseo J et al. (2014) Immigrant generation and diabetes risk among Mexican Americans: the Sacramento area Latino study on aging. Am J Public Health 104 Suppl 2:S234-50
Fejerman, Laura; Ahmadiyeh, Nasim; Hu, Donglei et al. (2014) Genome-wide association study of breast cancer in Latinas identifies novel protective variants on 6q25. Nat Commun 5:5260
Lee, Yeon-Shim; Moon, Ailee; Gomez, Cynthia (2014) Elder mistreatment, culture, and help-seeking: a cross-cultural comparison of older Chinese and Korean immigrants. J Elder Abuse Negl 26:244-69
Brewster, Paul W H; Melrose, Rebecca J; Marquine, María J et al. (2014) Life experience and demographic influences on cognitive function in older adults. Neuropsychology 28:846-58
Wong, Sabrina T; Wu, Amery; Gregorich, Steven et al. (2014) What Type of Social Support Influences Self-Reported Physical and Mental Health Among Older Women? J Aging Health 26:663-678

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