The overarching aim ofthe Program Development Core (PDC) is to provide pilot funding to support innovative and ground-breaking work on questions relating to population health. As outlined in our Center overview, major thematic/substantive areas of interest include: (1) elucidation of biological mechanisms (with increased emphasis on genetic/epigenetic processes), (2) life-course perspectives on population health (e.g., understanding eariy life and other cumulative influences on health trajectories, (3) increased understanding of cognitive aging across and within populations, and (4) international comparisons (e.g., to better understand population race/ethnic and SES health disparities). Paralleling our commitment to support for innovative science is our commitment to continued support for promising junior faculty, seeking to encourage the on-going development of a cadre of talented researchers focusing on interdisciplinary questions related to demography and population health as well as efforts to encourage talented, mid- (and even later) career faculty to incorporate a more bio-demographic focus to their program of research. To achieve these aims the PDC will work with the ARC to solicit and guide pilot projects.

Public Health Relevance

The pilot projects ofthe CBPH continue to improve our understanding of how individual biological risk factors, combinations of biological risk factors, and interactions of risk factors affect the length of life, the length of life with health problems, and the numbers of people with specific chronic conditions and disabilities. This understanding is central to planning for the future costs and needs of an aging population.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Center Core Grants (P30)
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Special Emphasis Panel (ZAG1-ZIJ-3)
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University of Southern California
Los Angeles
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Hu, Peifeng; Edenfield, Michael; Potter, Alan et al. (2015) Validation and modification of dried blood spot-based glycosylated hemoglobin assay for the longitudinal aging study in India. Am J Hum Biol 27:579-81
Vedhara, Kavita; Gill, Sana; Eldesouky, Lameese et al. (2015) Personality and gene expression: Do individual differences exist in the leukocyte transcriptome? Psychoneuroendocrinology 52:72-82
Levine, M E; Crimmins, E M (2014) Evidence of accelerated aging among African Americans and its implications for mortality. Soc Sci Med 118:27-32
Crimmins, Eileen; Kim, Jung Ki; McCreath, Heather et al. (2014) Validation of blood-based assays using dried blood spots for use in large population studies. Biodemography Soc Biol 60:38-48
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Ailshire, Jennifer A; Crimmins, Eileen M (2014) Fine particulate matter air pollution and cognitive function among older US adults. Am J Epidemiol 180:359-66
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Levine, Morgan; Crimmins, Eileen (2014) Not all smokers die young: a model for hidden heterogeneity within the human population. PLoS One 9:e87403

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