The Leadership and Administrative Core leads the vision for the science of frailty and its translation in this OAIC. It leads the identification of the next generation of research on frailty that should be created, supports research planning, recruitment of investigators, setting of goals and benchmarks, and evaluation activities for the Cores, the OAIC as a whole, conducts other administrative activities, and creates visibility for the accomplishments of the OAIC. Led by the Principal Investigator of this OAIC, in collaboration with the leaders of all other OAIC Cores and supported by administrative staff, the roles and responsibilities of this LAC include essential leadership in stimulating, planning, goal-setting, integrating, sustaining and monitoring OAIC operations, and the organization and evaluation of all elements of this proposed continuation of the Older Americans Independence Center at Johns Hopkins, as well as responsibility for setting standards, administration and reporting. Its goals are to ensure the conduct of these OAIC functions within a broader goal of helping recruit, initiate and nurture creation of a critical mass of investigators dedicated to advancing discoveries essential to prevention and treatment of frailty in older adults, and supporting the creation of innovative, high impact research to this end. The overall goals of workforce development and support of research are to translate the results of OAlC-supported work into new treatments to enhance independence in older Americans, and creation of a new generation of research leaders in the field.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
5P30AG021334-10
Application #
8378963
Study Section
Special Emphasis Panel (ZAG1-ZIJ-8)
Project Start
Project End
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
10
Fiscal Year
2012
Total Cost
$94,863
Indirect Cost
$36,926
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Ko, Fred; Abadir, Peter; Marx, Ruth et al. (2016) Impaired mitochondrial degradation by autophagy in the skeletal muscle of the aged female interleukin 10 null mouse. Exp Gerontol 73:23-7
Sun, Daniel Q; Huang, Jin; Varadhan, Ravi et al. (2016) Race and fall risk: data from the National Health and Aging Trends Study (NHATS). Age Ageing 45:120-7
Xue, Qian-Li; Tian, Jing; Fried, Linda P et al. (2016) Physical Frailty Assessment in Older Women: Can Simplification Be Achieved Without Loss of Syndrome Measurement Validity? Am J Epidemiol 183:1037-44
Abadir, Peter; Jain, Alka; Powell, Laura et al. (2016) Discovery and Validation of Agonistic Angiotensin Receptor Autoantibodies as Biomarkers of Adverse Outcomes. Circulation :
Gross, Alden L; Xue, Qian-Li; Bandeen-Roche, Karen et al. (2016) Declines and Impairment in Executive Function Predict Onset of Physical Frailty. J Gerontol A Biol Sci Med Sci 71:1624-1630
Cohen, Harvey J; Walston, Jeremy D; Rao, Sunil V et al. (2016) Renal Toxicity Associated with Salsalate in Elderly Adults with Anemia. J Am Geriatr Soc 64:898-9
Cooper, Zara; Rogers Jr, Selwyn O; Ngo, Long et al. (2016) Comparison of Frailty Measures as Predictors of Outcomes After Orthopedic Surgery. J Am Geriatr Soc 64:2464-2471
Tan, Jingwen; Liu, Shuiqing; Segal, Jodi B et al. (2016) Warfarin use and stroke, bleeding and mortality risk in patients with end stage renal disease and atrial fibrillation: a systematic review and meta-analysis. BMC Nephrol 17:157
Sweeney, Elizabeth M; Shinohara, Russell T; Dewey, Blake E et al. (2016) Relating multi-sequence longitudinal intensity profiles and clinical covariates in incident multiple sclerosis lesions. Neuroimage Clin 10:1-17
Semenov, Yevgeniy R; Bigelow, Robin T; Xue, Qian-Li et al. (2016) Association Between Vestibular and Cognitive Function in U.S. Adults: Data From the National Health and Nutrition Examination Survey. J Gerontol A Biol Sci Med Sci 71:243-50

Showing the most recent 10 out of 194 publications