Pilot research is vital for achieving the goals of the Oregon Roybal Center for Aging &Technology (ORCATECH). The overall objective of the ORCATECH Pilot Core is to support small-scale and innovative pilot projects that are consistent with our Center's theme - novel measurement and translation in behavioral and social science using pervasive computing technologies in the home and community. To this end our exemplary pilots focus on specific aspects of using pervasive computing to assess health and well-being outcomes. Major fundamental tenets for these pilots are to: 1) address key gaps in the process of creating new measurement methods in the field;2) facilitate translation by focusing on facilitating career development of junior investigators;and S) create a commons of pilot investigators coming together around interrelated project themes. In all cases, the expectation is that pilot projects will provide critical preliminary data that will lead to larger research and translation efforts. Six exemplary pilots are outlined consistent with these principles. These include: developing methodology to conduct culturally sensitive health and well-being measurements using technologies that may be unfamiliar to an older minority population (Pilot 1), integrated data analytics of large sets of multiple data streams to predict wellness status (Pilot 2), analysis of recurrence tolerance and other temporal aspects of online assessments relative to wellness status (Pilot S), developing everyday ambient measures of cognition and function (Pilot 4), mapping mobility patterns using a novel sensor system assessing multiple persons unobtrusively in personal spaces (Pilot 5), and relating night time activity to objective sensed activity and health behaviors and outcomes during subsequent days (Pilot 6). A natural training element is built into each pilot by pairing investigators early in their careers with those more experienced. Finally, the pilots'investigators will closely share their work with each other on an ongoing basis through the Data Forum and other ORCATECH venues.

Public Health Relevance

ORCATECH's Pilot Core is dedicated to the overall Center goal of facilitating optimal measurement of health and well-being for our aging population through advancing innovative in-home, always-on technologies. These new approaches hold tremendous promise to improve public health by providing highly sensitive, real-time, real-world information for more accurate timely diagnoses and individualized treatment and care.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Center Core Grants (P30)
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Special Emphasis Panel (ZAG1)
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Bhattacharyya, Partha
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Oregon Health and Science University
United States
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Leach, Julia M; Mancini, Martina; Kaye, Jeffrey A et al. (2018) Day-to-Day Variability of Postural Sway and Its Association With Cognitive Function in Older Adults: A Pilot Study. Front Aging Neurosci 10:126
Boespflug, Erin L; Simon, Matthew J; Leonard, Emmalyn et al. (2018) Targeted Assessment of Enlargement of the Perivascular Space in Alzheimer's Disease and Vascular Dementia Subtypes Implicates Astroglial Involvement Specific to Alzheimer's Disease. J Alzheimers Dis 66:1587-1597
Sano, Mary; Egelko, Susan; Zhu, Carolyn W et al. (2018) Participant satisfaction with dementia prevention research: Results from Home-Based Assessment trial. Alzheimers Dement 14:1397-1405
Kaye, Jeffrey; Reynolds, Christina; Bowman, Molly et al. (2018) Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data. J Vis Exp :
Teipel, Stefan; K├Ânig, Alexandra; Hoey, Jesse et al. (2018) Use of nonintrusive sensor-based information and communication technology for real-world evidence for clinical trials in dementia. Alzheimers Dement 14:1216-1231
Wardzala, Casia; Murchison, Charles; Loftis, Jennifer M et al. (2018) Sex differences in the association of alcohol with cognitive decline and brain pathology in a cohort of octogenarians. Psychopharmacology (Berl) 235:761-770
Seelye, Adriana; Mattek, Nora; Sharma, Nicole et al. (2018) Weekly observations of online survey metadata obtained through home computer use allow for detection of changes in everyday cognition before transition to mild cognitive impairment. Alzheimers Dement 14:187-194
Croff, Raina L; Witter Iv, Phelps; Walker, Miya L et al. (2018) Things Are Changing so Fast: Integrative Technology for Preserving Cognitive Health and Community History. Gerontologist :
Proulx, Jeffrey; Croff, Raina; Oken, Barry et al. (2018) Considerations for Research and Development of Culturally Relevant Mindfulness Interventions in American Minority Communities. Mindfulness (N Y) 9:361-370
Boespflug, Erin L; Schwartz, Daniel L; Lahna, David et al. (2018) MR Imaging-based Multimodal Autoidentification of Perivascular Spaces (mMAPS): Automated Morphologic Segmentation of Enlarged Perivascular Spaces at Clinical Field Strength. Radiology 286:632-642

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