RCDC The goal of the Research Career Development Core (RCDC) is to recruit, mentor and train future aging research leaders with skills in translational research and clinical Investigation focused on the Duke Pepper OAIC theme """"""""to understand and modify multiple pathways of functional decline"""""""". Promising early investigators will be recruited to develop and/or expand their investigative skills with an emphasis on translating basic research findings into clinical studies or taking clinical research findings and posing new basic research questions. RCDC Scholars will take courses tailored to their specific career needs, receive mentoring from a team of researchers with topic and/or aging research methodology expertise, and receive leadership training to prepare them for key positions in geriatrics and gerontology. Individual career development plans are created and regularly reviewed to ensure continued professional development. Our mentoring plan is designed to motivate clinical investigators to explore basic research principles and basic scientists to interface with clinical researchers. RCD Core awardees will participate in OAIC seminars and conferences where interdisciplinary investigators discuss their work;in this milieu ideas for collaborations are started and discussed, resulting in new projects and lines of inquiry. The RCDC will ensure that its awardees utilize resources from other OAIC research cores when appropriate, and that awardees present their findings in the Data Integration Working Group to optimize data integration across the Pepper Center. For each early investigator chosen as an RCDC Scholar the Duke Pepper OAlC's intended outcome is to prepare and support them to become independent investigators doing aging research. After two to three years of support, success for each RCDC Scholar will be measured by their completion of proposed research, publications, and ability to secure research career development or independent investigator-initiated extramural funding. RCD Core Project Leaders, Kenneth Lyles, MD and Cathleen Colon-Emeric, MD, MHS, will work especially closely with Pilot /Exploratory Core Studies Core Project Leader, Kenneth Schmader, MD, to maximize the use of our Core's resources to help prepare our awardees so they have the requisite skills and pilot data to successfully complete for new funding. Over the previous 19 years the RCDC has produced talented, well-trained investigators to help lead the next generation of scientists in clinical, translational or basic research that focuses on understanding and modifying pathways of functional decline.

Public Health Relevance

This Research Career Development Core in the Duke Pepper OAIC has the knowledge, skills, faculty, operations staff and resources necessary to recruit, select, mentor and train a cadre of clinical, translational and basic investigators critically needed in this country who will be capable of conducting research to maintain or restore independence in older persons

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
5P30AG028716-09
Application #
8695265
Study Section
Special Emphasis Panel (ZAG1-ZIJ-8)
Project Start
Project End
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
9
Fiscal Year
2014
Total Cost
$131,073
Indirect Cost
$47,587
Name
Duke University
Department
Type
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705
Anderson, Kristin A; Madsen, Andreas S; Olsen, Christian A et al. (2017) Metabolic control by sirtuins and other enzymes that sense NAD+, NADH, or their ratio. Biochim Biophys Acta 1858:991-998
Hatcher, Courtney C; Collins, Amber T; Kim, Sophia Y et al. (2017) Relationship between T1rho magnetic resonance imaging, synovial fluid biomarkers, and the biochemical and biomechanical properties of cartilage. J Biomech 55:18-26
Schaefer, Jonathan D; Scult, Matthew A; Caspi, Avshalom et al. (2017) Is low cognitive functioning a predictor or consequence of major depressive disorder? A test in two longitudinal birth cohorts. Dev Psychopathol :1-15
Gray, Shelly L; Hart, Laura A; Perera, Subashan et al. (2017) Meta-analysis of Interventions to Reduce Adverse Drug Reactions in Older Adults. J Am Geriatr Soc :
Hall, Rasheeda K (2017) Reply to: Comment on: ""Incorporating Geriatric Assessment into a Nephrology Clinic: Preliminary Data from Two Models of Care"". J Am Geriatr Soc 65:880
AbouAssi, Hiba; Connelly, Margery A; Bateman, Lori A et al. (2017) Does a lack of physical activity explain the rheumatoid arthritis lipid profile? Lipids Health Dis 16:39
Hsueh, M-F; Kraus, V B; Önnerfjord, P (2017) Cartilage matrix remodelling differs by disease state and joint type. Eur Cell Mater 34:70-82
Colón-Emeric, Cathleen S; Corazzini, Kirsten; McConnell, Eleanor et al. (2017) Study of Individualization and Bias in Nursing Home Fall Prevention Practices. J Am Geriatr Soc 65:815-821
Belsky, Daniel W; Caspi, Avshalom; Cohen, Harvey J et al. (2017) Impact of early personal-history characteristics on the Pace of Aging: implications for clinical trials of therapies to slow aging and extend healthspan. Aging Cell 16:644-651
Yin, Z; Fei, Z; Qiu, C et al. (2017) Dietary Diversity and Cognitive Function among Elderly People: A Population-Based Study. J Nutr Health Aging 21:1089-1094

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