The Biostatistics and Data Management Core (RC3) is one of four resource cores in the OAIC at the University of Florida. The mission ofthe UF OAIC is (1) to assess the risk factors and better understand the biological mechanisms of physical disability in older adults, (2) to develop and test effective prevention therapies, and (3) to educate and train new investigators in research on aging and disability, while developing their leadership qualities. The Biostatistics and Data Management Core is a key cog in the interaction between scientists from many disciplines to accomplish this mission. The core functions as both a data analysis resource and as a data coordinating center, involved in constructing data collection forms and managing the data (including quality control) for the studies conducted within the OAIC. In this capacity, the core maintains and updates the registry for the Recruitment, Adherence, and Retention Core (RC4) and tracks all research conducted within the OAIC with a web tracking system. The core is involved in all phases of these studies including initial study design and sample size calculations pre-proposal, randomization, and state-of-the-art statistical analyses once the data are completed. For study designs and data for which currently methodology is lacking, the core has the expertise to develop new state of the art methodology to perform correct and appropriate analyses of data collected in the Center. The Biostatistics and Data Management Core also is involved in preparation of manuscripts for dissemination within the research community. Finally, the Core serves as a key resource to the Junior Scholars of the Research Career Development Core (RCDC), providing consulting services and periodic special interest training topics, such as research methods, power analysis, analysis of incomplete data, principles of data management, and analysis of longitudinal data.

Public Health Relevance

The core ensures proper and efficient designs and analyses for all studies conducted to examine sarcopenia and aging. In addition, the core provides the interface to the UF&Shands research data repository which can be invaluable for recruiting, generating research hypotheses, and pilot studies. The core also provides essential training for junior investigators and Pepper Scholars on research design and statistical methods and analyses.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
5P30AG028740-07
Application #
8459408
Study Section
Special Emphasis Panel (ZAG1-ZIJ-8)
Project Start
Project End
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
7
Fiscal Year
2013
Total Cost
$87,924
Indirect Cost
$27,907
Name
University of Florida
Department
Type
DUNS #
969663814
City
Gainesville
State
FL
Country
United States
Zip Code
32611
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Anton, Stephen D; Embry, Chelsea; Marsiske, Michael et al. (2014) Safety and metabolic outcomes of resveratrol supplementation in older adults: results of a twelve-week, placebo-controlled pilot study. Exp Gerontol 57:181-7
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Cruz-Almeida, Yenisel; Black, Mieniecia L; Christou, Evangelos A et al. (2014) Site-specific differences in the association between plantar tactile perception and mobility function in older adults. Front Aging Neurosci 6:68
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Martin, A Daniel; Joseph, Anna-Marie; Beaver, Thomas M et al. (2014) Effect of intermittent phrenic nerve stimulation during cardiothoracic surgery on mitochondrial respiration in the human diaphragm. Crit Care Med 42:e152-6
Anton, Stephen D (2014) Can non-nutritive sweeteners enhance outcomes of weight loss interventions? Obesity (Silver Spring) 22:1413-4
Vaz Fragoso, Carlos A; Hsu, Fang-Chi; Brinkley, Tina et al. (2014) Combined reduced forced expiratory volume in 1 second (FEV1) and peripheral artery disease in sedentary elders with functional limitations. J Am Med Dir Assoc 15:665-70

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