The mission of the University of Florida Older Americans Independence Center (OAIC) is twofold: 1) to optimize older persons' physical performance and mobility through interdisciplinary approaches; and 2) to train new investigators in aging and disability research while developing their leadership qualities. Our goal is to enhance late-life health and independence, with a special focus on mobility. To accomplish our mission, our strategy is to attract studies and inventive investigators from diverse behavioral, clinical, basic, and technological science disciplines with a common research focus: ?mobility and prevention of disability.? Traversing the entire spectrum of biomedical investigation, including molecular biology, animal studies, clinical research, behavioral sciences, epidemiology, and engineering, our research effort addresses the OAIC's general goal: to increase scientific knowledge that leads to better ways to maintain or restore independence of older people. Our research objectives are to: 1) assess, using translational research (among diverse disciplines), the biological, co-morbid, psychosocial, behavioral, and other factors that contribute to physical function decline, loss of mobility, and progression toward disability; and 2) develop and reliably test, in clinical and preclinical studies, interventions that target mobility to prevent, delay, or recover the age-related declines in physical function. Our educational objective is to train future leaders in clinical translational research on aging. To meet these objectives the proposed OAIC trains Junior Scholars and supports investigators, resources, services, external studies, development projects, and pilot/exploratory studies through seven integrated cores: ? Leadership and Administrative Core; ? Research Education Core; ? Pilot/Exploratory Studies Core; ? Clinical Research Core; ? Metabolism and Translational Science Core; ? Biostatistics Core; and ? Data Science and Applied Technology Core. A relevant strength of the proposed OAIC is the concerted action of the interdisciplinary cores, projects, and investigators who address one common research focus spanning the entire spectrum of biomedical investigation.

Public Health Relevance

Better knowledge of the factors leading to optimizing mobility and developing efficacious and effective interventions to avert disability will have a major impact on practicing evidence-based geriatric medicine and public health.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
2P30AG028740-11
Application #
9163365
Study Section
Special Emphasis Panel (ZAG1-ZIJ-8 (M1))
Program Officer
Eldadah, Basil A
Project Start
2007-06-01
Project End
2022-03-31
Budget Start
2017-04-01
Budget End
2018-03-31
Support Year
11
Fiscal Year
2017
Total Cost
$1,023,397
Indirect Cost
$313,505
Name
University of Florida
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
969663814
City
Gainesville
State
FL
Country
United States
Zip Code
32611
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