The older population will more than double from 35 million in 2000 to 72 million in 2030 and comprise almost 20% of the U.S. population. To help avert the disability challenges these individuals will face, the University of Florida (UF) Older Americans Independence Center (OAIC) Research Education Core (REC) promotes the development of independent investigators in interdisciplinary research on aging related to older Americans' mobility. This core emphasizes the competency-based development of research and leadership skills for translating basic findings into clinical research and clinical findings into basic research. Key to this approach is our partnerships with UF's NIH-funded Clinical and Translational Science Institute (CTSI) and the Veterans Affairs (VA) Geriatric Research Education and Clinical Center (GRECC). Core resources are integrated with other internal and external sources for career support, including UF support; NIH and non-NIH career- development awards, minority supplements, research awards, and fellowships; and CTSI and VA support. The REC supports the research training of Junior Scholars who span the spectrum from beginning trainees not yet funded to advanced trainees who have competed successfully for career-development awards or grants that provide substantial salary support. Beginning Junior Scholars receive direct salary support from the REC to protect their time for career development and research. Advanced Junior Scholars may already have sufficient salary support but are eligible for REC mentorship, staff, Core support and travel resources, and REC training activities. In our first year, we propose eight Junior Scholars from four different UF Colleges (Nursing, Liberal Arts and Sciences, Public Health and Health Professions, and Medicine). Three Junior Scholars have clinical degrees and responsibilities; one is of Hispanic ethnicity; four are women and several have co-funding from key partners, their home departments, and/or extramural career development funding. The REC's overarching goal is to recruit, select, and train talented Junior Scholars committed to translational science and to integrating clinical insights of health/disease and independence/disability in older adults. Using their knowledge of advances in the basic sciences, these Junior Scholars will strive to improve clinical interventions that help the elderly avert mobility loss and maintain independence. We emphasize an interdisciplinary career-development plan that generates combined knowledge from a diverse cadre of scientists (basic, translational, social, behavioral, epidemiological, and clinical). Tailored career-development plans for each proposed REC-supported Junior Scholar, include, but are not limited to: a) a research project integrated with this OAIC's premise; b) a formal training strategy that stresses the integration of basic and clinical research and interactions across the OAIC research spectrum and the other OAIC Core facilities; c) a formal mentorship program that uses a team approach to foster basic and clinical science approaches; and d) a monitoring process to evaluate trainees' progress formally using specific milestones and achievements.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
2P30AG028740-11
Application #
9163373
Study Section
Special Emphasis Panel (ZAG1-ZIJ-8 (M1))
Project Start
Project End
Budget Start
2017-04-01
Budget End
2018-03-31
Support Year
11
Fiscal Year
2017
Total Cost
$143,643
Indirect Cost
$10,640
Name
University of Florida
Department
Type
Domestic Higher Education
DUNS #
969663814
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Ross, Kathryn M; Qiu, Peihua; You, Lu et al. (2018) Characterizing the Pattern of Weight Loss and Regain in Adults Enrolled in a 12-Week Internet-Based Weight Management Program. Obesity (Silver Spring) 26:318-323
Wanigatunga, Amal A; Manini, Todd M; Cook, Delilah R et al. (2018) Community-Based Activity and Sedentary Patterns Are Associated With Cognitive Performance in Mobility-Limited Older Adults. Front Aging Neurosci 10:341
Allen, Mariet; Wang, Xue; Burgess, Jeremy D et al. (2018) Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases. Alzheimers Dement 14:352-366
Wasson, Emily; Rosso, Andrea L; Santanasto, Adam J et al. (2018) Neural correlates of perceived physical and mental fatigability in older adults: A pilot study. Exp Gerontol 115:139-147
Horiguchi, Hiroyuki; Loftus, Tyler J; Hawkins, Russell B et al. (2018) Innate Immunity in the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome and Its Implications for Therapy. Front Immunol 9:595
Cavallari, Larisa H; Lee, Craig R; Beitelshees, Amber L et al. (2018) Multisite Investigation of Outcomes With Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention. JACC Cardiovasc Interv 11:181-191
Burke, Sara N; Gaynor, Leslie S; Barnes, Carol A et al. (2018) Shared Functions of Perirhinal and Parahippocampal Cortices: Implications for Cognitive Aging. Trends Neurosci 41:349-359
Sibille, Kimberly T; King, Christopher; Garrett, Timothy J et al. (2018) Omega-6: Omega-3 PUFA Ratio, Pain, Functioning, and Distress in Adults With Knee Pain. Clin J Pain 34:182-189
Tranah, Gregory J; Katzman, Shana M; Lauterjung, Kevin et al. (2018) Mitochondrial DNA m.3243A?>?G heteroplasmy affects multiple aging phenotypes and risk of mortality. Sci Rep 8:11887
White, Karessa; Kim, Mi-Jung; Han, Chul et al. (2018) Loss of IDH2 Accelerates Age-related Hearing Loss in Male Mice. Sci Rep 8:5039

Showing the most recent 10 out of 1197 publications