Data analysis in aging research poses distinctive challenges that require careful selection and tailoring of statistical methods, because of older adults'multiple comorbidities / medications, competing risks, and high dropout rates due to death or disability. In addition, in the current context of limited health care resources in the face of an impending surge in the number of older Americans, consideration has to be given to the cost effectiveness of interventions to restore or maintain the independence of older adults. ACEC will provide important guidance to OAIC researchers and projects, as well as other UCLA aging researchers, in the selection and conduct of appropriate statistical and economic analyses. The Analysis/Cost-Effectiveness Core will provide analytic support in research study design (selection of analytic strategy, and sample size/power issues), statistical data analysis, and interpretation and accurate description of findings, for: ? OAIC Career Development Awardees, ? OAIC supported pilots and development projects, ? UCLA junior researchers conducting research that meets UCLA OAIC mission, theme, and goals, ? Externally funded UCLA research projects that meet the UCLA OAIC mission, theme, and goals The core will also provide training workshops / tutorial seminars on state-of-the-art methods for statistical data analysis, comparative effectiveness studies, and cost effectiveness analysis. It will also assess the cost-effectiveness of successful clinical interventions studied in the OAIC Finally, the ACEC will disseminate new analytic approaches to comparative effectiveness studies, as they become available. , In collaboration with the other OAIC resource cores, ACEC will support externally funded aging research projects, promote aging research aimed at preventing disabilities and loss of independence in older ages, ensure the quality of its products, and nurture a new cohort of aging researchers and future leaders.
Rising disability rates in aging pre-boomer cohorts have increased the urgency for developing interventions aimed at preventing disability and maintaining the independence of aging Americans. Many segments of our population are at increased risk as a consequence of social stratification, economic stresses, obesity, and multiple chronic diseases. The Analysis and Cost Effectiveness resource core will provide technical analysis support to aging research in UCLA aimed at preventing morbidity and disability in vulnerable populations.
|Hernandez, Rosalba; Cheung, Elaine; Liao, Minli et al. (2017) The Association Between Depressive Symptoms and Cognitive Functioning in Older Hispanic/Latino Adults Enrolled in an Exercise Intervention. J Aging Health :898264317696776|
|Lee, A D; Spiegel, B M; Hays, R D et al. (2017) Gastrointestinal symptom severity in irritable bowel syndrome, inflammatory bowel disease and the general population. Neurogastroenterol Motil 29:|
|Lee, Yvonne C; Karlamangla, Arun S; Yu, Zhi et al. (2017) Pain Severity in Relation to the Final Menstrual Period in a Prospective Multiethnic Observational Cohort: Results From the Study of Women's Health Across the Nation. J Pain 18:178-187|
|Cho, Hyong Jin; Savitz, Jonathan; Dantzer, Robert et al. (2017) Sleep disturbance and kynurenine metabolism in depression. J Psychosom Res 99:1-7|
|Lê-Scherban, Félice; Brenner, Allison B; Hicken, Margaret T et al. (2017) Child and adult socioeconomic status and the cortisol response to acute stress: Evidence from the Multi-Ethnic Study of Atherosclerosis. Psychosom Med :|
|Tsai, Kim M; Dahl, Ronald E; Irwin, Michael R et al. (2017) The Roles of Parental Support and Family Stress in Adolescent Sleep. Child Dev :|
|Chiang, Jessica J; Bower, Julienne E; Irwin, Michael R et al. (2017) Adiposity moderates links from early adversity and depressive symptoms to inflammatory reactivity to acute stress during late adolescence. Brain Behav Immun 66:146-155|
|Chiang, Jessica J; Kim, Joanna J; Almeida, David M et al. (2017) Sleep Efficiency Modulates Associations Between Family Stress and Adolescent Depressive Symptoms and Negative Affect. J Adolesc Health 61:501-507|
|Bates-Jensen, Barbara M; McCreath, Heather E; Patlan, Anabel (2017) Subepidermal moisture detection of pressure induced tissue damage on the trunk: The pressure ulcer detection study outcomes. Wound Repair Regen 25:502-511|
|Lake, Jordan E; Popov, Mikhail; Post, Wendy S et al. (2017) Visceral fat is associated with brain structure independent of human immunodeficiency virus infection status. J Neurovirol 23:385-393|
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