Remarkable progress in genomic research is leading to a complete map of the building blocks of biology. Knowledge of this map is, in turn, fueling the study of gene regulation, where proteins often regulate their own production or that of other proteins in a complex web of interactions. An important challenge in post-genomic aging research will be the dissection and analysis of the complex gene regulatory networks involved in aging processes and function promoting anabolic therapies, and the deduction of phenotypic cellular responses from the structure and behavior of such networks. The implications of the underlying logic of genetic networks are difficult to deduce through experimental techniques alone, and successful approaches will, in many cases, involve the union of new experiments and computational modeling techniques.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
5P30AG031679-05
Application #
8378991
Study Section
Special Emphasis Panel (ZAG1-ZIJ-8)
Project Start
Project End
2014-05-31
Budget Start
2012-06-01
Budget End
2013-05-31
Support Year
5
Fiscal Year
2012
Total Cost
$74,568
Indirect Cost
$19,491
Name
Boston Medical Center
Department
Type
DUNS #
005492160
City
Boston
State
MA
Country
United States
Zip Code
02118
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