The statistical Data Enclave Core will support the growing need for methods that allow the distribution of useful public data that maintains confidentiality of study subjects. Specifically, this Core focuses on facilitating the use of data that is currently subject to various forms of confidentiality restrictions, thus increasing access to large-scale databases with complex phenotypes that are linked to administrative data, small area geographic data and biological and genetic data. A primary objective of the center is the development and application of leading-edge mathematical and statistical models for data masking for demographic datasets on aging.

Public Health Relevance

By developing new research areas, by supporting and enlarging the world's community of demographic scientists, and by developing new mathematical and statistical methods for the analysis of data related to the biodemography of aging as well as data management services, CPHA will advance understanding of the determinants of health, aging, and longevity.

Agency
National Institute of Health (NIH)
Type
Center Core Grants (P30)
Project #
2P30AG034424-06
Application #
8903599
Study Section
Special Emphasis Panel (ZAG1)
Program Officer
Haaga, John G
Project Start
Project End
Budget Start
Budget End
Support Year
6
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Duke University
Department
Type
DUNS #
City
Durham
State
NC
Country
United States
Zip Code
27705
Yashin, Anatoliy I; Arbeev, Konstantin G; Arbeeva, Liubov S et al. (2016) How the effects of aging and stresses of life are integrated in mortality rates: insights for genetic studies of human health and longevity. Biogerontology 17:89-107
Yashin, Anatoliy I; Zhbannikov, Ilya; Arbeeva, Liubov et al. (2016) Pure and Confounded Effects of Causal SNPs on Longevity: Insights for Proper Interpretation of Research Findings in GWAS of Populations with Different Genetic Structures. Front Genet 7:188
Yashin, Anatoliy I; Arbeev, Konstantin G; Wu, Deqing et al. (2016) How Genes Modulate Patterns of Aging-Related Changes on the Way to 100: Biodemographic Models and Methods in Genetic Analyses of Longitudinal Data. N Am Actuar J 20:201-232
Arbeev, Konstantin G; Ukraintseva, Svetlana V; Yashin, Anatoliy I (2016) Dynamics of biomarkers in relation to aging and mortality. Mech Ageing Dev 156:42-54
Schoeni, Robert F; Bianchi, Suzanne M; Hotz, V Joseph et al. (2015) Intergenerational transfers and rosters of the extended family: a new substudy of the Panel Study of Income Dynamics. Longit Life Course Stud 6:319-330
Vestergaard, Sonja; Thinggaard, Mikael; Jeune, Bernard et al. (2015) Physical and mental decline and yet rather happy? A study of Danes aged 45 and older. Aging Ment Health 19:400-8
Lea, Amanda J; Altmann, Jeanne; Alberts, Susan C et al. (2015) Developmental constraints in a wild primate. Am Nat 185:809-21
Yashin, Anatoliy I; Wu, Deqing; Arbeeva, Liubov S et al. (2015) Genetics of aging, health, and survival: dynamic regulation of human longevity related traits. Front Genet 6:122
Arbeev, Konstantin G; Akushevich, Igor; Kulminski, Alexander M et al. (2014) Joint Analyses of Longitudinal and Time-to-Event Data in Research on Aging: Implications for Predicting Health and Survival. Front Public Health 2:228
Lea, Amanda J; Learn, Niki H; Theus, Marcus J et al. (2014) Complex sources of variance in female dominance rank in a nepotistic society. Anim Behav 94:87-99

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