The Pilot Core B will support one of the principal mechanisms by which the Boston Roybal Center (BRC) will achieve its overarching goal to develop and test behavior change strategies that promote healthy aging, especially for persons at high risk for poor health outcomes. The thematic focus of the BRC is on novel interventions to increase physical activity in vulnerable middle-aged and older adults. The Pilot Core will achieve this goal by supporting a group of innovative and scientifically rigorous pilot studies that will enhance our knowledge base, inform each other with new research methodologies and tools, and ultimately work collaboratively to develop the pilot data and experience necessary to conduct future full-scale clinical trials. The Pilot Core will leverage the knowledge gained by each project, incrementally enriching our conceptual model, and ultimately developing successful interventions to achieve health-promoting behavior change in at-risk populations.
The specific aims of the Core are 1) To solicit, select, and support 4-6 of the most meritorious pilot studies each year that advance the BRC goals. These pilot studies will be solicited from among postdoctoral trainees, junior faculty, and established investigators of all racial and ethnic backgrounds who are working in participating BRC institutions. 2) To use the knowledge and skills gained by each pilot project to develop new research grants that test behavior change strategies to promote healthy aging in people at risk of poor health outcomes. We will also share results and plan ancillary studies by conducting monthly interactive seminars, and hosting an annual Visiting Scholar and Scientific Dinner focused on mechanisms to achieve sustainable health-promoting behavior changes. 3) To enhance the progress of pilot awardees'research projects by requiring the awardees to present their work at monthly seminars and External Advisory Committee meetings, and conducting biannual Center meetings between pilot investigators. Center faculty, and Core A and B leaders. 4) To assure the scientific integrity of our research and the safety of human subjects. The extensive research and administrative experience of the Co-Leaders and large pool of collaborating, investigators at participating institutions will help assure the Core's success. The Pilot Core will work closely with the Management and Administrative Core to make sure the BRC operates smoothly and fulfills its aims.

Public Health Relevance

Drawing on the broad talent of investigators in five Boston-area universities, the Boston Roybal Center will conduct pilot studies to translate research findings to promote an active lifestyle, especially among those at greatest risk for poor health. The findings will provide valuable insights into motivational and behavioral strategies that can be used to design larger interventions to improve health and well-being in later life.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Center Core Grants (P30)
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Special Emphasis Panel (ZAG1)
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King, Jonathan W
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Brandeis University
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Jimison, Holly B; Hagler, Stuart; Kurillo, Gregorij et al. (2015) Remote health coaching for interactive exercise with older adults in a home environment. Conf Proc IEEE Eng Med Biol Soc 2015:5485-8
Pavel, Misha; Jimison, Holly B; Korhonen, Ilkka et al. (2015) Behavioral Informatics and Computational Modeling in Support of Proactive Health Management and Care. IEEE Trans Biomed Eng 62:2763-75