The UW-FHCRC CFAR International Core strives to optimize efficiencies by leveraging diverse global HIV research projects, increasing collaborations and networking, mentoring new US and international investigators, optimizing infrastructure in international settings, and facilitating new research directions. During the past decades. International Core researchers have contributed substantive research to identify effective HIV interventions. In the new 5-year cycle, the International Core is poised to develop a new portfolio of collaborative implementation research that will translate efficacy research to implementation scale-up. The Core will foster synergies between ongoing NIH-supported HIV research projects, promote demonstration projects of interventions and facilitate training and mentorship to determine cost-effectiveness as interventions are implemented.
Our specific aims are:
AIM 1 : To facilitate research to address cutting-edge global HIV issues. We will emphasize implementation science in pilot awards, and promote research on combination HIV prevention, chronic treatment, and vulnerable populations. We will establish a new sub-Core on Economic Evaluation, partnering with the Bill and Melinda Gates Foundation to determine sustainability and cost considerations for implementation.
AIM 2 : To strategically expand and leverage collaborations and research projects. We will extend collaborations from mature partners (Kenya, Peru) to new partners including regional neighbor countries;in addition, we will leverage activities of relevant UW DGH Centers (HAI, l-TECH, Global WACh) and Seattle global health organizations (BMGF, PATH) to facilitate research by CFAR investigators. We will provide infrastructure and co-develop training for international sites with other UW-FHCRC CFAR Cores, including SPRC, Biostatistics and AAlMS. We will support inter-CFAR initiatives: specifically, the Women and HIV and sub-Saharan Africa inter-CFAR collaborations.
AIM 3 : To sustain investment in new investigators and broaden the scope of international partnerships. We will provide support for trainees and join with the Developmental core to support a new Mentored International Investigator Award. We will provide mentoring workshops, and provide accessible mentorship to new international trainees. During the past 5 years, the International Core has realized appreciable return on investment in publications, grants, and new global HIV research leaders. We anticipate expanded relevance and efficiencies directly paralleling needs as the global HIV response transitions from emergent to sustainable strategies
sustainable strategies. RELEVANCE (See instructions): With 33 million HIV-infected individuals worldwide and continued new HIV infections, it remains critical to optimize HIV prevention and chronic treatment, and to develop mechanisms to translate efficacy research to scaled implementation, incorporating a vision that includes sustainability. The International Core will advance research of direct relevance to global HIV by supporting new investigators, enhancing collaborations, pilot and infrastructure support, and providing innovative training and mentorin
|Dombrowski, Julia C; Carey, James W; Pitts, Nicole et al. (2016) HIV provider and patient perspectives on the Development of a Health Department "Data to Care" Program: a qualitative study. BMC Public Health 16:491|
|Wang, Kerong; Chen, Wei-Ti; Zhang, Lin et al. (2016) Facilitators of and barriers to HIV self-management: Perspectives of HIV-positive women in China. Appl Nurs Res 32:91-97|
|Dross, Sandra E; Munson, Paul V; Kim, Se Eun et al. (2016) Kinetics of Myeloid-Derived Suppressor Cell Frequency and Function during Simian Immunodeficiency Virus Infection, Combination Antiretroviral Therapy, and Treatment Interruption. J Immunol :|
|Yang, Cui; Crane, Heidi M; Cropsey, Karen et al. (2016) Implementation of Computer-delivered Brief Alcohol Intervention in HIV Clinical Settings: Who Agrees to Participate? J Addict Res Ther 7:|
|Kohler, Pamela K; Tippett Barr, Beth A; KangÊ¼ombe, Anderson et al. (2016) Safety, Feasibility, and Acceptability of the PrePex Device for Adult Male Circumcision in Malawi. J Acquir Immune Defic Syndr 72 Suppl 1:S49-55|
|Hien, Ha Thuc Ai; Thanh, Tran Tan; Thu, Nguyen Thi Mai et al. (2016) Development and evaluation of a real-time polymerase chain reaction assay for the rapid detection of Talaromyces marneffei MP1 gene in human plasma. Mycoses :|
|Levine, Molly; Beck, Ingrid; Styrchak, Sheila et al. (2016) Comparison of Matrix-Based and Filter Paper-Based Systems for Transport of Plasma for HIV-1 RNA Quantification and Amplicon Preparation for Genotyping. J Clin Microbiol 54:1899-901|
|Kerani, Roxanne P; Herbeck, Joshua T; Buskin, Susan E et al. (2016) Evidence of Local HIV Transmission in the African Community of King County, Washington. J Immigr Minor Health :|
|Wilson, Kate S; Wanje, George; Yuhas, Krista et al. (2016) A Prospective Study of Intimate Partner Violence as a Risk Factor for Detectable Plasma Viral Load in HIV-Positive Women Engaged in Transactional Sex in Mombasa, Kenya. AIDS Behav 20:2065-77|
|Akullian, Adam N; Mukose, Aggrey; Levine, Gillian A et al. (2016) People living with HIV travel farther to access healthcare: a population-based geographic analysis from rural Uganda. J Int AIDS Soc 19:20171|
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