Abstract

The DAB CFAR Developmental Core has made a significant impact on HIV/AIDS research programs since the inception of the Center in 1988. The primary tool of the Developmental Core is the Developmental Grant Program which funds peer reviewed intramural HIV/AIDS related research grants targeted to junior faculty members and investigators new to the HIV/AIDS field. Since the inception of this program, a total of $2.069.115 were used to competitively fund 87 Developmental grants, selected from a total of 235 applications submitted to the UAB CFAR Developmental Grant Program. This investment has yielded $65.537.542 in extramural grant direct cost funding for a return on investment of $31 for every $1 of Developmental Grant Program money. This value has been maintained over the last funding period with $20 per every 1 of CFAR Developmental grant money. Embedded in the Developmental Grant Program is the core's mentoring program. Applicants are provided an experienced mentor from the CFAR Executive Board or CFAR Core Director in a related research area to the proposed project.
The Specific Aims of the Developmental core are:
Specific Aim 1. Specific Aim 2. To continue to administer the highly successful CFAR Developmental Grant Program. The Developmental Core will continue to fund 4 high quality proposals each year. A mentoring program will be provided to each of the awardees. The Core will also facilitate development of IRGs designed to bring new HIV/AIDS research to the CFAR. To provide faculty development resources to HIV/AIDS investigators. The Developmental Core will provide services to facilitate grant submission and review. The Core will also implement new educational opportunities to graduate students and fellows to become familiar with HIV/AIDS research. The Developmental Core will continue to play an integral part in the continued vitality of the HIV/AIDS research endeavor. During the next funding period, several innovative, new programs will be developed to support CFAR interdisciplinary research groups (IRG) and individual UAB CFAR investigators.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI027767-24
Application #
8379102
Study Section
Special Emphasis Panel (ZAI1-SV-A)
Project Start
Project End
Budget Start
2012-06-01
Budget End
2013-05-31
Support Year
24
Fiscal Year
2012
Total Cost
$1,107,390
Indirect Cost
$346,782

  Institution

Name
University of Alabama Birmingham
Department
Type
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294

  Publications

Peng, Binghao J; Carlson, Jonathan M; Liu, Michael K P et al. (2018) Antisense-Derived HIV-1 Cryptic Epitopes Are Not Major Drivers of Viral Evolution during the Acute Phase of Infection. J Virol 92:
Shi, Bi; Geng, Jianlin; Wang, Yin-Hu et al. (2018) Foxp1 Negatively Regulates T Follicular Helper Cell Differentiation and Germinal Center Responses by Controlling Cell Migration and CTLA-4. J Immunol 200:586-594
Moshiri, Niema; Mirarab, Siavash (2018) A Two-State Model of Tree Evolution and Its Applications to Alu Retrotransposition. Syst Biol 67:475-489
Crockett, Kaylee B; Rice, Whitney S; Turan, Bulent (2018) Associations Between Multiple Forms of Discrimination and Tobacco Use Among People Living With HIV: The Mediating Role of Avoidance Coping. J Acquir Immune Defic Syndr 78:9-15
Mai, Uyen; Mirarab, Siavash (2018) TreeShrink: fast and accurate detection of outlier long branches in collections of phylogenetic trees. BMC Genomics 19:272
Tomalka, Amanda G; Resto-Garay, Ivelisse; Campbell, Kerry S et al. (2018) In vitro Evidence That Combination Therapy With CD16-Bearing NK-92 Cells and FDA-Approved Alefacept Can Selectively Target the Latent HIV Reservoir in CD4+ CD2hi Memory T Cells. Front Immunol 9:2552
Ram, Daniel R; Manickam, Cordelia; Hueber, Brady et al. (2018) Tracking KLRC2 (NKG2C)+ memory-like NK cells in SIV+ and rhCMV+ rhesus macaques. PLoS Pathog 14:e1007104
AIDS-defining Cancer Project Working Group of IeDEA, COHERE in EuroCoord (2018) Non-Hodgkin lymphoma risk in adults living with HIV across five continents. AIDS 32:2777-2786
Rice, Whitney S; Logie, Carmen H; Napoles, Tessa M et al. (2018) Perceptions of intersectional stigma among diverse women living with HIV in the United States. Soc Sci Med 208:9-17
Elion, Richard A; Althoff, Keri N; Zhang, Jinbing et al. (2018) Recent Abacavir Use Increases Risk of Type 1 and Type 2 Myocardial Infarctions Among Adults With HIV. J Acquir Immune Defic Syndr 78:62-72

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