UAB CFAR Mission: To support UAB and affiliated investigators in the conduct of multidisciplinary, cutting-edge research in the prevention, pathogenesis, therapeutics, clinical care, and psychosocial manifestations of HIV and related disorders in the United States and around the world. The UAB CFAR was established in 1988 as one of the original seven charter centers of a new NIH initiative. From the outset, the UAB CFAR has played a national and international leadership role in basic, translational, and clinical HIV/AIDS research. With seminal research discoveries spanning the gamut from HIV-1 viral dynamics to viral diversity to the zoonotic origins of HIV-1, and with translational therapeutics research leading to first-in-human trials, and ultimately FDA approval, of no fewer than 7 antiretroviral drugs, the UAB CFAR and its members have played an instrumental role in leading HIV/AIDS research efforts on a global scale for twenty years. Remarkably, with the exception of Dr. Eric Hunter who recently left the institution, the core scientific leadership of the UAB CFAR including Drs. Michael S. Saag (Experimental Therapeutics and current CFAR Director), Beatrice H. Hahn (Virus Discovery and current CFAR Co-Director), George M. Shaw (Viral Pathogenesis and current CFAR Associate Director), and Casey Morrow (Molecular Virology and current CFAR Associate Director and Developmental Core Leader), has remained intact since the inception of the UAB CFAR. This leadership group has spearheaded and nurtured a major HIV/AIDS research agenda for over twenty years and has fostered the recruitment and development of a new generation of HIV/AIDS investigators at UAB. What will become evident in this revised application is that the UAB CFAR continues to provide scientific leadership, programmatic coordination, essential research support services training in scientific methodologies, effective communication, targeted faculty recruitment, and linkages between investigators working in widely diverse areas of research in a manner that makes UAB HIV/AIDS research important today as it has been for the past twenty years

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI027767-25
Application #
8495863
Study Section
Special Emphasis Panel (ZAI1-SV-A)
Project Start
Project End
Budget Start
2013-06-01
Budget End
2014-05-31
Support Year
25
Fiscal Year
2013
Total Cost
$332,701
Indirect Cost
$105,602
Name
University of Alabama Birmingham
Department
Type
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Rice, Whitney S; Logie, Carmen H; Napoles, Tessa M et al. (2018) Perceptions of intersectional stigma among diverse women living with HIV in the United States. Soc Sci Med 208:9-17
Elion, Richard A; Althoff, Keri N; Zhang, Jinbing et al. (2018) Recent Abacavir Use Increases Risk of Type 1 and Type 2 Myocardial Infarctions Among Adults With HIV. J Acquir Immune Defic Syndr 78:62-72
Fredericksen, R J; Gibbons, L; Brown, S et al. (2018) Medication understanding among patients living with multiple chronic conditions: Implications for patient-reported measures of adherence. Res Social Adm Pharm 14:540-544
Stoll, Matthew L; Weiss, Pamela F; Weiss, Jennifer E et al. (2018) Age and fecal microbial strain-specific differences in patients with spondyloarthritis. Arthritis Res Ther 20:14
Subramaniam, Akila; Van Der Pol, William J; Ptacek, Travis et al. (2018) Midtrimester microbial DNA variations in maternal serum of women who experience spontaneous preterm birth. J Matern Fetal Neonatal Med :1-9
Kay, Emma S; Rice, Whitney S; Crockett, Kaylee B et al. (2018) Experienced HIV-Related Stigma in Health Care and Community Settings: Mediated Associations With Psychosocial and Health Outcomes. J Acquir Immune Defic Syndr 77:257-263
Xu, Wanli; Luo, Zhenwu; Alekseyenko, Alexander V et al. (2018) Distinct systemic microbiome and microbial translocation are associated with plasma level of anti-CD4 autoantibody in HIV infection. Sci Rep 8:12863
Smith, Samuel R; Schaaf, Kaitlyn; Rajabalee, Nusrah et al. (2018) The phosphatase PPM1A controls monocyte-to-macrophage differentiation. Sci Rep 8:902
Wang, Yong; Schafer, Cara C; Hough, Kenneth P et al. (2018) Myeloid-Derived Suppressor Cells Impair B Cell Responses in Lung Cancer through IL-7 and STAT5. J Immunol 201:278-295
Jones, Robert B; Dorsett, Kaitlyn A; Hjelmeland, Anita B et al. (2018) The ST6Gal-I sialyltransferase protects tumor cells against hypoxia by enhancing HIF-1? signaling. J Biol Chem 293:5659-5667

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