Specific Aims 1. To facilitate the implementation of patient oriented HIV/AIDS related research at UCLA 2. To assist investigators with the regulatory aspects of biomedical and behavioral patient-oriented research 3. To establish and maintain a clinical database that will interface with the CFAR/CNICS program. The primary responsibility of the Clinical Research Facilitation Core is to facilitate the process of IRB submissions for faculty, fellows, new researchers and translational researchers who do not have a great deal of experience with human subjects research. While funding to facilities and equipment are crucial to the conduct of research, regulatory delays in the conduct of research are often overlooked. This core in itself is innovative as it provides investigators with resources not previously available to reduce delays. By its very nature, this core will support new initiatives. It will encourage research among new faculty, young faculty and fellows. The core is fully linked into the CFAR seed grant process and allows recipients to become productive in their research far earlier than if they did not have the Core to assist them. The Core has created both a website and a blog to share the resources learned while submitting applications. Additionally, the Core provides seminars to investigators and staff to increase knowledge of regulatory pitfalls and procedures. In reducing regulatory delays in. the conduct of patient-oriented research, this Core helps to maintain UCLA investigators on the cutting edge of research in HIV. PERFORMANCE SITE(S) (organization, city, state) University of California, Los Angeles Center for Clinical AIDS Research and Education 9911 W. Pico Blvd. Suite 980 Los Angeles, CA 90035 PHS 398 (Rev. 04/06) 614

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI028697-23
Application #
8377991
Study Section
Special Emphasis Panel (ZAI1-EC-A)
Project Start
Project End
2013-03-04
Budget Start
2012-03-01
Budget End
2013-02-28
Support Year
23
Fiscal Year
2012
Total Cost
$134,684
Indirect Cost
$27,010
Name
University of California Los Angeles
Department
Type
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Lowe, Emily; Truscott, Laurel C; De Oliveira, Satiro N (2016) In Vitro Generation of Human NK Cells Expressing Chimeric Antigen Receptor Through Differentiation of Gene-Modified Hematopoietic Stem Cells. Methods Mol Biol 1441:241-51
Epeldegui, Marta; Lee, Jeannette Y; Martínez, Anna C et al. (2016) Predictive Value of Cytokines and Immune Activation Biomarkers in AIDS-Related Non-Hodgkin Lymphoma Treated with Rituximab plus Infusional EPOCH (AMC-034 trial). Clin Cancer Res 22:328-36
Lake, Jordan E; Popov, Mikhail; Post, Wendy S et al. (2016) Visceral fat is associated with brain structure independent of human immunodeficiency virus infection status. J Neurovirol :
Peckham-Gregory, Erin C; Thapa, Dharma R; Martinson, Jeremy et al. (2016) MicroRNA-related polymorphisms and non-Hodgkin lymphoma susceptibility in the Multicenter AIDS Cohort Study. Cancer Epidemiol 45:47-57
Tsai, Alexander C; Tomlinson, Mark; Comulada, W Scott et al. (2016) Food insufficiency, depression, and the modifying role of social support: Evidence from a population-based, prospective cohort of pregnant women in peri-urban South Africa. Soc Sci Med 151:69-77
Tsai, Alexander C; Tomlinson, Mark; Comulada, W Scott et al. (2016) Intimate Partner Violence and Depression Symptom Severity among South African Women during Pregnancy and Postpartum: Population-Based Prospective Cohort Study. PLoS Med 13:e1001943
Shimizu, Saki; Yadav, Swati Seth; An, Dong Sung (2016) Stable Delivery of CCR5-Directed shRNA into Human Primary Peripheral Blood Mononuclear Cells and Hematopoietic Stem/Progenitor Cells via a Lentiviral Vector. Methods Mol Biol 1364:235-48
Deng, Yun; Zhao, Jian; Sakurai, Daisuke et al. (2016) Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production. Ann Rheum Dis 75:2007-2013
Liu, Sandy; Cadaneanu, Radu M; Zhang, Baohui et al. (2016) Keratin 13 Is Enriched in Prostate Tubule-Initiating Cells and May Identify Primary Prostate Tumors that Metastasize to the Bone. PLoS One 11:e0163232
Ramirez, Christina M; Sinclair, Elizabeth; Epling, Lorrie et al. (2016) Immunologic profiles distinguish aviremic HIV-infected adults. AIDS 30:1553-62

Showing the most recent 10 out of 778 publications