The UCLA CFAR Developmental Core provides seed funding for innovative research projects as well as training for submission and review of NIH- style applications. These grants, which allow investigators to obtain the preliminary data they need to support R01 applications or program projects, are an increasingly important aspect of the UCLA CFAR's overall activities as other sources of potential funding, including federal sources, have reduced their allocations. New and junior investigators, in particular, require support in order to establish a productive scientific career. Collaborative research projects are especially encouraged by our CFAR, to bring about the fruitful juxtaposition of techniques, ideas, and concepts from different labs and disciplines.
The Specific Aims for the Developmental Core are: 1. To provide a mechanism for rapid review and concise application of high-quality, innovative research projects. 2. To develop RFAs for seed funding of promising projects in important and timely areas of AIDS research. 3. To develop RFAs to support and mentor investigators at the level of graduate, post-graduate, "transitional," and new facultyand, as necessary, to retain existing faculty. 4. To develop a mechanism for creating venues that encourage and facilitate close collaboration and novel approaches to AIDS research. These venues include, but are not limited to, think tanks, conferences, and seminars. 5. To mentor and prepare seed grant applicants in the process of preparing successful grant applications. 6. To supplement the activities of the above four aims through private-fund raising efforts.
This aim i s coordinated in part by the Administrative core, in collaboration with the UCLA AIDS Institute. No support is requested here.

Public Health Relevance

The Developmental Core aims to promote research in ways that cannot be easily supported by individual research grants;i.e. providing modest grants to young/new investigators through a competitive review process, by mentoring these investigators at a critical time in their careers and by supporting collaborative research efforts of all Faculty through symposia, think tanks and community outreach events.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI028697-25
Application #
8631022
Study Section
Special Emphasis Panel (ZAI1-UKS-A)
Project Start
Project End
Budget Start
2014-03-01
Budget End
2015-02-28
Support Year
25
Fiscal Year
2014
Total Cost
$961,110
Indirect Cost
$192,851
Name
University of California Los Angeles
Department
Type
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Lake, Jordan E; Popov, Mikhail; Post, Wendy S et al. (2016) Visceral fat is associated with brain structure independent of human immunodeficiency virus infection status. J Neurovirol :
Lowe, Emily; Truscott, Laurel C; De Oliveira, Satiro N (2016) In Vitro Generation of Human NK Cells Expressing Chimeric Antigen Receptor Through Differentiation of Gene-Modified Hematopoietic Stem Cells. Methods Mol Biol 1441:241-51
Epeldegui, Marta; Lee, Jeannette Y; Martínez, Anna C et al. (2016) Predictive Value of Cytokines and Immune Activation Biomarkers in AIDS-Related Non-Hodgkin Lymphoma Treated with Rituximab plus Infusional EPOCH (AMC-034 trial). Clin Cancer Res 22:328-36
Tsai, Alexander C; Tomlinson, Mark; Comulada, W Scott et al. (2016) Intimate Partner Violence and Depression Symptom Severity among South African Women during Pregnancy and Postpartum: Population-Based Prospective Cohort Study. PLoS Med 13:e1001943
Peckham-Gregory, Erin C; Thapa, Dharma R; Martinson, Jeremy et al. (2016) MicroRNA-related polymorphisms and non-Hodgkin lymphoma susceptibility in the Multicenter AIDS Cohort Study. Cancer Epidemiol 45:47-57
Tsai, Alexander C; Tomlinson, Mark; Comulada, W Scott et al. (2016) Food insufficiency, depression, and the modifying role of social support: Evidence from a population-based, prospective cohort of pregnant women in peri-urban South Africa. Soc Sci Med 151:69-77
Liu, Sandy; Cadaneanu, Radu M; Zhang, Baohui et al. (2016) Keratin 13 Is Enriched in Prostate Tubule-Initiating Cells and May Identify Primary Prostate Tumors that Metastasize to the Bone. PLoS One 11:e0163232
Shimizu, Saki; Yadav, Swati Seth; An, Dong Sung (2016) Stable Delivery of CCR5-Directed shRNA into Human Primary Peripheral Blood Mononuclear Cells and Hematopoietic Stem/Progenitor Cells via a Lentiviral Vector. Methods Mol Biol 1364:235-48
Deng, Yun; Zhao, Jian; Sakurai, Daisuke et al. (2016) Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production. Ann Rheum Dis 75:2007-2013
Ramirez, Christina M; Sinclair, Elizabeth; Epling, Lorrie et al. (2016) Immunologic profiles distinguish aviremic HIV-infected adults. AIDS 30:1553-62

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