The Design &Analysis Core (Core F) is the source for epidemiologic and statistical design and analyses expertise as well as data collection and management services to support the research of the members of the Baylor-UTHouston CFAR. Core F was established in 1994 and continues to meet the needs of CFAR members as evidenced from needs assessment surveys. The specific goals of Core F are: (1) to provide epidemiologic and statistical design and analysis support for AIDS-related research;(2) to advise the development of new AIDS investigators by providing assistance in study design, statistical analysis, IRB and GCRC applications, and grant writing;(3) to support investigators in establishing procedures for development and management of research-study-specific databases to be conducive to efficient epidemiologic and statistical analyses;(4) to provide study design and analysis leadership in collaboration with basic, behavioral, and clinical sciences investigators as well as with investigators from the Baylor and UTHouston institutions;and (5) to synergize with CFAR program areas and other Cores to interweave the design and analysis services into those areas and to utilize the scientific expertise of the Core to meet program aims. A high priority of Core F is assisting new investigators with the process of research study design and development. With early and timely collaboration with Core F, feasible research designs and robust epidemiologic and statistical analyses can be planned. Sufficient computer facilities and software are available to manage the current needs of CFAR investigators;anticipated charge-back funds can be used for future needs. Core F operates under standard policies and procedures with guidance from the Core's Oversight Committee, the CFAR Internal Advisory Committee, and the CFAR External Advisory Board. In addition, Core F will be evaluated regularly to determine the effectiveness of the core services and functions.

Public Health Relevance

The Center for AIDS Research (CFAR) at Baylor-UTHouston supports research on the pathogenesis, prevention, detection, and treatment of HIV infection and AIDS. The CFAR has been an essential catalyst for HIV/AIDS research in the Houston area. The State of Texas ranks fourth in the total number of AIDS cases in the United States. The Design &Analysis Core helps researchers with experimental design and interpretation of data.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (ZAI1-JBS-A)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Baylor College of Medicine
United States
Zip Code
Kadmon, Claudine S; Landers, Cameron T; Li, Haiyan S et al. (2017) MicroRNA-22 controls interferon alpha production and erythroid maturation in response to infectious stress in mice. Exp Hematol 56:7-15
Temereanca, Aura; Oprea, Cristiana; Wertheim, Joel O et al. (2017) HIV transmission clusters among injecting drug users in Romania. Romanian biotechnological letters 22:12307-12315
Lietman, Caressa D; Lim, Joohyun; Grafe, Ingo et al. (2017) Fkbp10 Deletion in Osteoblasts Leads to Qualitative Defects in Bone. J Bone Miner Res 32:1354-1367
Yeh, Szu-Ying; Huang, Wei-Hsiang; Wang, Wei et al. (2017) Respiratory Network Stability and Modulatory Response to Substance P Require Nalcn. Neuron 94:294-303.e4
He, Huan; Xue, Jing; Wang, Weiming et al. (2017) Efficient Transduction of Human and Rhesus Macaque Primary T Cells by a Modified Human Immunodeficiency Virus Type 1-Based Lentiviral Vector. Hum Gene Ther 28:271-285
Vernetti, Lawrence; Gough, Albert; Baetz, Nicholas et al. (2017) Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle. Sci Rep 7:42296
Lo, Yuan-Hung; Chung, Eunah; Li, Zhaohui et al. (2017) Transcriptional Regulation by ATOH1 and its Target SPDEF inĀ theĀ Intestine. Cell Mol Gastroenterol Hepatol 3:51-71
Yang, Lina; Liu, Li; Gao, Hong et al. (2017) The stem cell factor SALL4 is an essential transcriptional regulator in mixed lineage leukemia-rearranged leukemogenesis. J Hematol Oncol 10:159
Huo, Yanling; Patel, Kunjal; Scott, Gwendolyn B et al. (2017) Lymphocyte subsets in HIV-exposed uninfected infants and HIV-unexposed uninfected infants. J Allergy Clin Immunol 140:605-608.e3
Kaiser, Philipp; Joshi, Sunil K; Kim, Peggy et al. (2017) Assays for precise quantification of total (including short) and elongated HIV-1 transcripts. J Virol Methods 242:1-8

Showing the most recent 10 out of 649 publications