Overview - The UCSD Center for AIDS Research (CFAR) engages, synergizes and serves investigators at UCSD (including the Veterans Medical Research Foundation of the San Diego VA Healthcare System), The Scripps Research Institute, the Salk Institute, and the La Jolla Institute for Allergy and Immunology. Since 1994, the CFAR has enhanced HIV/AIDS activities at the participating institutions and the San Diego community by 1) encouraging young faculty and investigators new to HIV/AIDS research through Developmental Grant Awards;2) providing expert advice and services in a number of specialized research areas through the CFAR Cores, and 3) fostering research interactions and community wide education through mentoring, training. Scientific Focus Groups, education, and outreach programs.
The specific aims of the UCSD CFAR are to a) provide development and implementation of innovative HIV research and the foundation and framework for highly productive collaborations across disciplines, investigators, and our four member institutions, b) provide training, inspiration, mentoring, and expert guidance (TIME) to trainees and junior and international investigators, c) create scientific cores that extend the scientific reach of CFAR investigators, d) capitalize on our international expertise, proximity to Mexico and MEPI programs to create locally sustainable HIV research programs in targeted resource limited settings, e) foster collaborations across CFARs for NIH-funded programs and initiatives, and f) develop a strategic plan for the growth of the CFAR and to flexibly adapt to a constantly evolving research environment. Since our renewal in 2007, these efforts are yielding a productive, enthusiastic and growing group of investigators. As the synergy between our investigators and member institutions increases, we have identified the need to expand our infrastructure to address new and expanding opportunities. We have added new faculty members and expanded scientific interactions with local institutions. The revised and improved CFAR is comprised of nine Cores: Administrative, Developmental, Flow Cytometry, Genomics and Sequencing, Clinical Investigation and Biostatistics, Protein Expression and Proteomics, International, Translational Virology, and Bioinformatics and Information Technologies. We continue to be guided by our External Advisory and Executive Committees, as well as the CFAR Director and Co-Directors, Core Directors, Scientific Focus Groups and our membership.

Public Health Relevance

The UCSD CFAR supports basic, clinical and translational research programs at UCSD and at our member institutions. In addition to our active, productive and groundbreaking research, we have a remarkable program for fostering the development of junior faculty and investigators new to HIV research.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
2P30AI036214-19A1
Application #
8490495
Study Section
Special Emphasis Panel (ZAI1-UKS-A (J1))
Program Officer
Namkung, Ann S
Project Start
1994-04-01
Project End
2018-03-31
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
19
Fiscal Year
2013
Total Cost
$3,083,697
Indirect Cost
$496,271
Name
University of California San Diego
Department
Pathology
Type
Schools of Medicine
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
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Szumowski, Suzannah C; Botts, Michael R; Popovich, John J et al. (2014) The small GTPase RAB-11 directs polarized exocytosis of the intracellular pathogen N. parisii for fecal-oral transmission from C. elegans. Proc Natl Acad Sci U S A 111:8215-20
Hepler, N Lance; Scheffler, Konrad; Weaver, Steven et al. (2014) IDEPI: rapid prediction of HIV-1 antibody epitopes and other phenotypic features from sequence data using a flexible machine learning platform. PLoS Comput Biol 10:e1003842
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Murrell, Ben; Murrell, Daniel; Murrell, Hugh (2014) R2-equitability is satisfiable. Proc Natl Acad Sci U S A 111:E2160
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Wang, Cathy X; Sather, Blythe D; Wang, Xuefeng et al. (2014) Rapamycin relieves lentiviral vector transduction resistance in human and mouse hematopoietic stem cells. Blood 124:913-23
Jeong, Su Jin; Kim, Min Hyung; Song, Je Eun et al. (2014) Short communication: prospective comparison of qualitative versus quantitative polymerase chain reaction for monitoring virologic treatment failure in HIV-infected patients. AIDS Res Hum Retroviruses 30:827-9
Wertheim, Joel O; Smith, Martin D; Smith, Davey M et al. (2014) Evolutionary origins of human herpes simplex viruses 1 and 2. Mol Biol Evol 31:2356-64

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