Overview - The UCSD Center for AIDS Research (CFAR) engages, synergizes and serves investigators at UCSD (including the Veterans Medical Research Foundation of the San Diego VA Healthcare System), The Scripps Research Institute, the Salk Institute, and the La Jolla Institute for Allergy and Immunology. Since 1994, the CFAR has enhanced HIV/AIDS activities at the participating institutions and the San Diego community by 1) encouraging young faculty and investigators new to HIV/AIDS research through Developmental Grant Awards;2) providing expert advice and services in a number of specialized research areas through the CFAR Cores, and 3) fostering research interactions and community wide education through mentoring, training. Scientific Focus Groups, education, and outreach programs.
The specific aims of the UCSD CFAR are to a) provide development and implementation of innovative HIV research and the foundation and framework for highly productive collaborations across disciplines, investigators, and our four member institutions, b) provide training, inspiration, mentoring, and expert guidance (TIME) to trainees and junior and international investigators, c) create scientific cores that extend the scientific reach of CFAR investigators, d) capitalize on our international expertise, proximity to Mexico and MEPI programs to create locally sustainable HIV research programs in targeted resource limited settings, e) foster collaborations across CFARs for NIH-funded programs and initiatives, and f) develop a strategic plan for the growth of the CFAR and to flexibly adapt to a constantly evolving research environment. Since our renewal in 2007, these efforts are yielding a productive, enthusiastic and growing group of investigators. As the synergy between our investigators and member institutions increases, we have identified the need to expand our infrastructure to address new and expanding opportunities. We have added new faculty members and expanded scientific interactions with local institutions. The revised and improved CFAR is comprised of nine Cores: Administrative, Developmental, Flow Cytometry, Genomics and Sequencing, Clinical Investigation and Biostatistics, Protein Expression and Proteomics, International, Translational Virology, and Bioinformatics and Information Technologies. We continue to be guided by our External Advisory and Executive Committees, as well as the CFAR Director and Co-Directors, Core Directors, Scientific Focus Groups and our membership.

Public Health Relevance

The UCSD CFAR supports basic, clinical and translational research programs at UCSD and at our member institutions. In addition to our active, productive and groundbreaking research, we have a remarkable program for fostering the development of junior faculty and investigators new to HIV research.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
2P30AI036214-19A1
Application #
8490495
Study Section
Special Emphasis Panel (ZAI1-UKS-A (J1))
Program Officer
Namkung, Ann S
Project Start
1994-04-01
Project End
2018-03-31
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
19
Fiscal Year
2013
Total Cost
$3,083,697
Indirect Cost
$496,271
Name
University of California San Diego
Department
Pathology
Type
Schools of Medicine
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Mills, Jon C; Harman, Jeffrey S; Cook, Robert L et al. (2017) Comparative effectiveness of dual vs. single-action antidepressants on HIV clinical outcomes in HIV-infected people with depression. AIDS 31:2515-2524
Hoenigl, Martin; Braun, Dominique L; Kouyos, Roger et al. (2017) Evaluation of the Predictive Potential of the Short Acute Retroviral Syndrome Severity Score for HIV-1 Disease Progression in Individuals With Acute HIV Infection. J Acquir Immune Defic Syndr 74:e114-e117
Morris, Sheldon R; Zhao, Mitchell; Smith, Davey M et al. (2017) Longitudinal Viral Dynamics in Semen During Early HIV Infection. Clin Infect Dis 64:428-434
Wagner, Gabriel A; Landais, Elise; Caballero, Gemma et al. (2017) Intrasubtype B HIV-1 Superinfection Correlates with Delayed Neutralizing Antibody Response. J Virol 91:
Monroe, Anne K; Fleishman, John A; Voss, Cindy C et al. (2017) Assessing Antiretroviral Use During Gaps in HIV Primary Care Using Multisite Medicaid Claims and Clinical Data. J Acquir Immune Defic Syndr 76:82-89
Chaillon, Antoine; Nakazawa, Masato; Wertheim, Joel O et al. (2017) No Substantial Evidence for Sexual Transmission of Minority HIV Drug Resistance Mutations in Men Who Have Sex with Men. J Virol 91:
Hartzler, Bryan; Carlini, Beatriz H; Newville, Howard et al. (2017) Identifying HIV care enrollees at-risk for cannabis use disorder. AIDS Care 29:846-850
Akrami, Kevan; Coletta, Joelle; Mehta, Sanjay et al. (2017) Gordonia sternal wound infection treated with ceftaroline: case report and literature review. JMM Case Rep 4:e005113
Gianella, Sara; Taylor, Jeff; Brown, Timothy R et al. (2017) Can research at the end of life be a useful tool to advance HIV cure? AIDS 31:1-4
Spies, Georgina; Fennema-Notestine, Christine; Cherner, Mariana et al. (2017) Changes in cognitive function in women with HIV infection and early life stress. AIDS Care 29:14-23

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