Core I - The CFAR International Core facilitates collaborative HIV/AIDS research activities involving CFAR members and their international colleagues by providing logistical, administrative and technical support;strategic planning;and seed funding.
The specific AIMS of the CFAR International Core are as follows: 1. Enhance existing collaborations and facilitate new ones between the CFAR research community and investigators working in resource-limited settings. 2. Facilitate the development of preliminary data in resource-limited settings to support more extensive externally funded research projects and programs. 3. Create opportunities for international researchers based in resource-limited settings to gain first-rate technical skills and establish professional connections with CFAR investigators. The International Core provides centralized administrative and logistical support to CFAR members to reduce delays in launching international research projects. Our International Pilot grants provide seed funds to foreign investigators in collaboration with CFAR members for research leading to more extensive investigations. Our Visiting Researchers and Travel grant programs facilitate the exchange of scholars between UCSD and institutions in our target countries. We organize and host an Annual Research Day to showcase international research undertaken by CFAR members and their foreign collaborators. Our Research Day increases the visibility of our CFAR's international research and helps disseminate research that is timely and topical to the San Diego HIV/AIDS research community.

Public Health Relevance

Two-thirds of the HIV pandemic is centered in Africa, 15% in Asia, and <5% in North America. The UCSD CFAR International Core supports research and training opportunities for foreign researchers in 7 middle and low-income countries to improve their capacity to respond to their local HIV epidemics, and to generate preliminary data for publications and proposals in partnership with CFAR collaborators.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Center Core Grants (P30)
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Special Emphasis Panel (ZAI1-UKS-A (J1))
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University of California San Diego
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Heaton, Robert K; Franklin Jr, Donald R; Deutsch, Reena et al. (2015) Neurocognitive change in the era of HIV combination antiretroviral therapy: the longitudinal CHARTER study. Clin Infect Dis 60:473-80
Hepler, N Lance; Scheffler, Konrad; Weaver, Steven et al. (2014) IDEPI: rapid prediction of HIV-1 antibody epitopes and other phenotypic features from sequence data using a flexible machine learning platform. PLoS Comput Biol 10:e1003842
Szumowski, Suzannah C; Botts, Michael R; Popovich, John J et al. (2014) The small GTPase RAB-11 directs polarized exocytosis of the intracellular pathogen N. parisii for fecal-oral transmission from C. elegans. Proc Natl Acad Sci U S A 111:8215-20
Murrell, Ben; Murrell, Daniel; Murrell, Hugh (2014) R2-equitability is satisfiable. Proc Natl Acad Sci U S A 111:E2160
Grant, Igor; Franklin Jr, Donald R; Deutsch, Reena et al. (2014) Asymptomatic HIV-associated neurocognitive impairment increases risk for symptomatic decline. Neurology 82:2055-62
Blattner, Claudia; Lee, Jeong Hyun; Sliepen, Kwinten et al. (2014) Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers. Immunity 40:669-80
Cachay, Edward R (2014) The forgotten component in the staging and management of HIV/hepatitis C virus-coinfected patients. Clin Infect Dis 59:320-1
Jeong, Su Jin; Kim, Min Hyung; Song, Je Eun et al. (2014) Short communication: prospective comparison of qualitative versus quantitative polymerase chain reaction for monitoring virologic treatment failure in HIV-infected patients. AIDS Res Hum Retroviruses 30:827-9
Wang, Cathy X; Sather, Blythe D; Wang, Xuefeng et al. (2014) Rapamycin relieves lentiviral vector transduction resistance in human and mouse hematopoietic stem cells. Blood 124:913-23
Scheffler, Konrad; Murrell, Ben; Kosakovsky Pond, Sergei L (2014) On the validity of evolutionary models with site-specific parameters. PLoS One 9:e94534

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