Core B - The developmental component of the UCSD CFAR is designed to facilitate and encourage new investigators and new ideas in HIV/AIDS research. The intent is to optimize opportunities for productive research by providing immediate financial support in association with resource support provided by the Core facilities. Three categories of developmental grants will be supported, although the number and type of these categories are flexible: (1) foster junior investigators;(2) support newly-recruited faculty involved with HIV-related research;and (3) respond rapidly to evolving research opportunities. Requests for submission of developmental grants are advertised through the Administrative Core twice a year for funding in January and July. Faculty at all four CFAR member institutions are eligible to apply. The submissions are evaluated by an expert review committee and additional ad hoc reviewers who are experts in the pertinent fields as needed. Scientific merit is the primary criterion for making the awards;however, fostering the development of junior investigators is an important programmatic goal that is also considered in prioritization of awards. The maximum amount for the awards currently given is $50,000 for unfunded junior investigators and $30,000 for others. Grants to senior investigators must receive prior approval from the NIAID CFAR Program Office. As part of their award, investigators are required to provide documentation of publications and peer-reviewed funding that result from the developmental awards. They are also required to cite CFAR developmental funds in publications resulting from work supported by developmental grants. The Developmental Core also coordinates the NCI-funded pilot grants in HIV malignancies, in partnership with the UCSD Moores Cancer Center. The CFAR and Cancer Center issue joint requests for applications and conduct joint reviews. The Developmental Core coordinates the CFAR portion of this collaboration. The Developmental Core has an active and effective mentorship program. With the growth of the CFAR, anticipate a greater number of innovative and timely projects will be funded, attracting new members and affiliates who can advance HIV and AIDS research.
The CFAR Developmental Core provides critical funding for developmental projects, particularly to junior investigators. The funding and mentorship offered through the Developmental Core generate innovative research and pilot data for investigators to publish and to use to generate larger grant applications.
|Heaton, Robert K; Franklin Jr, Donald R; Deutsch, Reena et al. (2015) Neurocognitive change in the era of HIV combination antiretroviral therapy: the longitudinal CHARTER study. Clin Infect Dis 60:473-80|
|Szumowski, Suzannah C; Botts, Michael R; Popovich, John J et al. (2014) The small GTPase RAB-11 directs polarized exocytosis of the intracellular pathogen N. parisii for fecal-oral transmission from C. elegans. Proc Natl Acad Sci U S A 111:8215-20|
|Hepler, N Lance; Scheffler, Konrad; Weaver, Steven et al. (2014) IDEPI: rapid prediction of HIV-1 antibody epitopes and other phenotypic features from sequence data using a flexible machine learning platform. PLoS Comput Biol 10:e1003842|
|Grant, Igor; Franklin Jr, Donald R; Deutsch, Reena et al. (2014) Asymptomatic HIV-associated neurocognitive impairment increases risk for symptomatic decline. Neurology 82:2055-62|
|Murrell, Ben; Murrell, Daniel; Murrell, Hugh (2014) R2-equitability is satisfiable. Proc Natl Acad Sci U S A 111:E2160|
|Cachay, Edward R (2014) The forgotten component in the staging and management of HIV/hepatitis C virus-coinfected patients. Clin Infect Dis 59:320-1|
|Blattner, Claudia; Lee, Jeong Hyun; Sliepen, Kwinten et al. (2014) Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers. Immunity 40:669-80|
|Wang, Cathy X; Sather, Blythe D; Wang, Xuefeng et al. (2014) Rapamycin relieves lentiviral vector transduction resistance in human and mouse hematopoietic stem cells. Blood 124:913-23|
|Jeong, Su Jin; Kim, Min Hyung; Song, Je Eun et al. (2014) Short communication: prospective comparison of qualitative versus quantitative polymerase chain reaction for monitoring virologic treatment failure in HIV-infected patients. AIDS Res Hum Retroviruses 30:827-9|
|Wertheim, Joel O; Smith, Martin D; Smith, Davey M et al. (2014) Evolutionary origins of human herpes simplex viruses 1 and 2. Mol Biol Evol 31:2356-64|
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