The CFAR Immune Function Core makes available sophisticated immunologic services to CFAR researchers at all levels of expertise. The Core facilitates access to reagents, state-of-the-art instrumentation and performs complex immunological assays in response to user requests.
The specific aims of the Immune Function core are: ? To operate, maintain and provide access to a wide array of instruments needed for modern immunology including multi-color flow cytometers, plate readers, imaging, bead array reader. ? To perform a wide range of immunological assays including ELISA, ELISPOT, multi-plexed cytokine levels, western blotting, and flow cytometry in response to user requests ? To provide access to discount purchasing of reagents, kits and antibodies and access to immunologic reagents available in small test quantifies ? To provide training on instrument use and consultation about the design of immunological assays
Understanding of HIV immunology is important for vaccine development, disease pathogenesis and immune restoration in HIV disease. This core provides services to CFAR faculty who require access to flow cytometry and other methods for evaluating immune functions.
|Longenecker, Chris T; Jiang, Ying; Orringer, Carl E et al. (2014) Soluble CD14 is independently associated with coronary calcification and extent of subclinical vascular disease in treated HIV infection. AIDS 28:969-77|
|Mbonye, Uri; Karn, Jonathan (2014) Transcriptional control of HIV latency: cellular signaling pathways, epigenetics, happenstance and the hope for a cure. Virology 454-455:328-39|
|Gibson, Richard M; Meyer, Ashley M; Winner, Dane et al. (2014) Sensitive deep-sequencing-based HIV-1 genotyping assay to simultaneously determine susceptibility to protease, reverse transcriptase, integrase, and maturation inhibitors, as well as HIV-1 coreceptor tropism. Antimicrob Agents Chemother 58:2167-85|
|Chiu, Yen-Ling; Shan, Liang; Huang, Hailiang et al. (2014) Sprouty-2 regulates HIV-specific T cell polyfunctionality. J Clin Invest 124:198-208|
|Mukherjee, Pranab K; Chandra, Jyotsna; Retuerto, Mauricio et al. (2014) Oral mycobiome analysis of HIV-infected patients: identification of Pichia as an antagonist of opportunistic fungi. PLoS Pathog 10:e1003996|
|Chandra, Jyotsna; Pearlman, Eric; Ghannoum, Mahmoud A (2014) Animal models to investigate fungal biofilm formation. Methods Mol Biol 1147:141-57|
|Olvera-García, Gustavo; Espinosa, Enrique; Sieg, Scott F et al. (2014) Cytomegalovirus-specific responses of CD38? memory T cells are skewed towards IFN-? and dissociated from CD154 in HIV-1 infection. AIDS 28:311-6|
|Tabler, Caroline O; Lucera, Mark B; Haqqani, Aiman A et al. (2014) CD4+ memory stem cells are infected by HIV-1 in a manner regulated in part by SAMHD1 expression. J Virol 88:4976-86|
|Zapanta Rinonos, Serendipity; Rai, Urvashi; Vereb, Sydney et al. (2014) Sequential logic of polarity determination during the haploid-to-diploid transition in Saccharomyces cerevisiae. Eukaryot Cell 13:1393-402|
|Hulgan, Todd; Boger, M Sean; Liao, Diana H et al. (2014) Urinary eicosanoid metabolites in HIV-infected women with central obesity switching to raltegravir: an analysis from the women, integrase, and fat accumulation trial. Mediators Inflamm 2014:803095|
Showing the most recent 10 out of 320 publications