The Lifespan/Tufts/Brown CFAR was established in 1998 as a collaboration between Brown University and Tufts University and their affiliated hospitals. Since the Initial CFAR award in 1998, we have successfully competed for two renewals, and met our stated benchmarks and milestones throughout the 12 years since the Initial award. We have revised our goals as the epidemic and its treatment have evolved, and steadily increased the interdisciplinary research essential to further progress in this area. This CFAR serves as the basis for extensive collaborative, interdisciplinary research among the CFAR members, and has served as the leading force in developing and supporting relevant new initiatives. This application emphasizes the return on investment of funding cross-disciplinary HIV research throughout Brown and Tufts Universities, their affiliated hospitals, and partner institutions in the developing world. In accordance with directives in the NIH CFAR PAR, we have developed a multidisciplinary environment that supports basic, clinical, epidemiologic, behavioral and translational research in the detection, prevention, and treatment of HIV infection and AIDS. This application emphasizes our progress toward this mission over the past four years, and its proposed activities over the next five years. If this application proves to be successful. Looking ahead, we Intend to further emphasize multi-institutional, cross-disciplinary studies related to HIV/AIDS both in New England and In Sub-Saharan Africa and Asia, with continuing support for our established CFAR Scientific Programs In International HIV/AIDS and in Prisoner Health and Human Rights for cross-disciplinary work In our Scientific Working Groups related to neurocognitive aspects of HIV and its treatment, cardiovascular and metabolic consequences of HIV and antiretroviral therapy In our aging population of persons living with HIV, and further multidisciplinary studies of the consequences of alcohol and other substances of abuse on HIV acquisition and response to treatment.

Public Health Relevance

Despite advances In HIV/AIDS treatment and prevention, the disease continues to ravage many lives. Our CFARs ultimate goal is to Improve the lives of people living with HIV and prevent new Infections by serving as a basis for extensive collaborative, multi and Interdisciplinary research. The development of junior investigators within the field is crucial to stemming this epidemic.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Center Core Grants (P30)
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Special Emphasis Panel (ZAI1-RRS-A (J1))
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Namkung, Ann S
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Miriam Hospital
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Joppa, Meredith C; Rizzo, Christie J; Nieves, Amethys V et al. (2016) Pilot Investigation of the Katie Brown Educational Program: A School-Community Partnership. J Sch Health 86:288-97
Genberg, Becky L; Hogan, Joseph W; Braitstein, Paula (2016) Home testing and counselling with linkage to care. Lancet HIV 3:e244-6
Kwara, Awewura; Enimil, Anthony; Gillani, Fizza S et al. (2016) Pharmacokinetics of First-Line Antituberculosis Drugs Using WHO Revised Dosage in Children With Tuberculosis With and Without HIV Coinfection. J Pediatric Infect Dis Soc 5:356-365
Bloomfield, Gerald S; DeLong, Allison K; Akwanalo, Constantine O et al. (2016) Markers of Atherosclerosis, Clinical Characteristics, and Treatment Patterns in Heart Failure: A Case-Control Study of Middle-Aged Adult Heart Failure Patients in Rural Kenya. Glob Heart 11:97-107
Kohli, Rakhi; Winston, Diana; Sheehan, Heidi et al. (2016) Cholesterol Levels in HIV- and/or HCV-Infected Drug Users Living in Argentina. J Int Assoc Provid AIDS Care 15:400-5
Okafor, Chukwuemeka N; Kelso, Natalie E; Bryant, Vaughn et al. (2016) Body mass index, inflammatory biomarkers and neurocognitive impairment in HIV-infected persons. Psychol Health Med :1-14
Chan, Philip A; Glynn, Tiffany R; Oldenburg, Catherine E et al. (2016) Implementation of Preexposure Prophylaxis for Human Immunodeficiency Virus Prevention Among Men Who Have Sex With Men at a New England Sexually Transmitted Diseases Clinic. Sex Transm Dis 43:717-723
Mullins, Tanya L Kowalczyk; Zimet, Gregory; Lally, Michelle et al. (2016) Adolescent Human Immunodeficiency Virus Care Providers' Attitudes Toward the Use of Oral Pre-Exposure Prophylaxis in Youth. AIDS Patient Care STDS 30:339-48
Hoffmann, Michael; MacCarthy, Sarah; Batson, Ashley et al. (2016) Barriers along the care cascade of HIV-infected men in a large urban center of Brazil. AIDS Care 28:57-62
Operario, Don; Gamarel, Kristi E; Iwamoto, Mariko et al. (2016) Couples-Focused Prevention Program to Reduce HIV Risk Among Transgender Women and Their Primary Male Partners: Feasibility and Promise of the Couples HIV Intervention Program. AIDS Behav :

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