The overarching goal of the Clinical Core is to provide the 'value added'expertise, space, services, and training that current and future HIV/AIDS investigators need to support, enhance, and strengthen their clinical and translational research. We will accomplish this through activities that support the following Specific Aims:
Aim 1 : Facilitate the conduct of scientifically rigorous HIV/AIDS clinical and translational research. Rationale: Scientifically rigorous empirical research is the foundation upon which trust in biomedical interventions and clinical standards of care for the prevention and treatment of HIV/AIDS is based.
Aim 2 : Provide clinical data and human specimens for use in HIV-related research. Rationale: HIV/AIDS research goals are achieved more rapidly and at less expense if clinical data and materials are available to a broad range of investigators for rapid search and retrieval from a central source.
Aim 3 : Support the development of the next generation of clinical and translational HIV/AIDS researchers. Rationale: Continued advances in biomedical prevention and clinical care for people with, or at-risk for, HIV/AIDS will only be possible if specialized training is continually made available to researchers newly entering the field.
Aim 4 : Make current and future clinical and translational researchers aware of expertise, space, services, and training available through the Core. Rationale: Providing information about resources that will facilitate the advance of, and overcome barriers to, HIV/AIDS research will help grow the base of investigators actively working in the field.
Aim 4 : Make current and future clinical and translational researchers aware of expertise, space, services, and training available through the Core. Rationale: Providing information about resources that will facilitate the advance of, and overcome barriers to, HIV/AIDS research will help grow the base of investigators actively working in the field
Research among people infected or at risk for HIV is critical to eliminating AIDS. The CFAR Clinical Core has a major impact on facilitating HIV research at Emory and beyond. The Core enhances and facilitates human HIV research by NIH-funded scientists at Emory and Atlanta partner institutions. Also, particular attention is given to supporting young and new investigators entering the field of HIV/AIDS research in people.
|Kelley, Colleen F; Lai, Lilin; Ibegbu, Chris et al. (2016) Differences in expression of gut-homing receptors on CD4+ T cells in black and white HIV-negative men who have sex with men. AIDS 30:1305-8|
|Anderson, Albert M; Lennox, Jeffrey L; Nguyen, Minh L et al. (2016) Preliminary study of a novel cognitive assessment device for the evaluation of HIV-associated neurocognitive impairment. J Neurovirol 22:816-822|
|Kannanganat, Sunil; Wyatt, Linda S; Gangadhara, Sailaja et al. (2016) High Doses of GM-CSF Inhibit Antibody Responses in Rectal Secretions and Diminish Modified Vaccinia Ankara/Simian Immunodeficiency Virus Vaccine Protection in TRIM5Î±-Restrictive Macaques. J Immunol 197:3586-3596|
|HernÃ¡ndez-Romieu, Alfonso C; del Rio, Carlos; HernÃ¡ndez-Ãvila, Juan Eugenio et al. (2016) CD4 Counts at Entry to HIV Care in Mexico for Patients under the ""Universal Antiretroviral Treatment Program for the Uninsured Population,"" 2007-2014. PLoS One 11:e0152444|
|White, Darcy; Grey, Jeremy A; Gorbach, Pamina M et al. (2016) Racial Differences in Partnership Attributes, Typologies, and Risk Behaviors Among Men Who Have Sex With Men in Atlanta, Georgia. Arch Sex Behav :|
|Kalokhe, Ameeta S; Ibegbu, Chris C; Kaur, Surinder P et al. (2016) INTIMATE PARTNER VIOLENCE IS ASSOCIATED WITH INCREASED CD4(+) T-CELL ACTIVATION AMONG HIV-NEGATIVE HIGH-RISK WOMEN. Pathog Immun 1:193-213|
|Ravindran, Rajesh; Loebbermann, Jens; Nakaya, Helder I et al. (2016) The amino acid sensor GCN2 controls gut inflammation by inhibiting inflammasome activation. Nature 531:523-7|
|Nasri, Hashem; Kabbani, Sarah; Bou Alwan, Melhim et al. (2016) Retrospective Study of Cryptococcal Meningitis With Elevated Minimum Inhibitory Concentration to Fluconazole in Immunocompromised Patients. Open Forum Infect Dis 3:ofw076|
|Sun, Xiaoyan; Peng, Limin; Huang, Yijian et al. (2016) Generalizing Quantile Regression for Counting Processes with Applications to Recurrent Events. J Am Stat Assoc 111:145-156|
|MÃ³naco, Daniela C; Dilernia, Dario A; Fiore-Gartland, Andrew et al. (2016) Balance between transmitted HLA preadapted and nonassociated polymorphisms is a major determinant of HIV-1 disease progression. J Exp Med 213:2049-63|
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