The overarching goal of the Clinical Core is to provide the 'value added'expertise, space, services, and training that current and future HIV/AIDS investigators need to support, enhance, and strengthen their clinical and translational research. We will accomplish this through activities that support the following Specific Aims:
Aim 1 : Facilitate the conduct of scientifically rigorous HIV/AIDS clinical and translational research. Rationale: Scientifically rigorous empirical research is the foundation upon which trust in biomedical interventions and clinical standards of care for the prevention and treatment of HIV/AIDS is based.
Aim 2 : Provide clinical data and human specimens for use in HIV-related research. Rationale: HIV/AIDS research goals are achieved more rapidly and at less expense if clinical data and materials are available to a broad range of investigators for rapid search and retrieval from a central source.
Aim 3 : Support the development of the next generation of clinical and translational HIV/AIDS researchers. Rationale: Continued advances in biomedical prevention and clinical care for people with, or at-risk for, HIV/AIDS will only be possible if specialized training is continually made available to researchers newly entering the field.
Aim 4 : Make current and future clinical and translational researchers aware of expertise, space, services, and training available through the Core. Rationale: Providing information about resources that will facilitate the advance of, and overcome barriers to, HIV/AIDS research will help grow the base of investigators actively working in the field.
Aim 4 : Make current and future clinical and translational researchers aware of expertise, space, services, and training available through the Core. Rationale: Providing information about resources that will facilitate the advance of, and overcome barriers to, HIV/AIDS research will help grow the base of investigators actively working in the field

Public Health Relevance

Research among people infected or at risk for HIV is critical to eliminating AIDS. The CFAR Clinical Core has a major impact on facilitating HIV research at Emory and beyond. The Core enhances and facilitates human HIV research by NIH-funded scientists at Emory and Atlanta partner institutions. Also, particular attention is given to supporting young and new investigators entering the field of HIV/AIDS research in people.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI050409-15
Application #
8470522
Study Section
Special Emphasis Panel (ZAI1-RRS-A)
Project Start
Project End
Budget Start
2013-08-01
Budget End
2014-07-31
Support Year
15
Fiscal Year
2013
Total Cost
$356,998
Indirect Cost
$134,703
Name
Emory University
Department
Type
DUNS #
066469933
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Moody, Raymond L; Starks, Tyrel J; Grov, Christian et al. (2018) Internalized Homophobia and Drug Use in a National Cohort of Gay and Bisexual Men: Examining Depression, Sexual Anxiety, and Gay Community Attachment as Mediating Factors. Arch Sex Behav 47:1133-1144
Woodson, Evonne; Goldberg, Alec; Michelo, Clive et al. (2018) HIV transmission in discordant couples in Africa in the context of antiretroviral therapy availability. AIDS 32:1613-1623
Bratcher, Anna; Schlueter Wirtz, Susan; Siegler, Aaron J (2018) Users of a National Directory of PrEP Service Providers: Beliefs, Self-Efficacy, and Progress Toward Prescription. J Acquir Immune Defic Syndr 78:e28-e30
Anderson, Albert M; Easley, Kirk A; Kasher, Nicole et al. (2018) Neurofilament light chain in blood is negatively associated with neuropsychological performance in HIV-infected adults and declines with initiation of antiretroviral therapy. J Neurovirol 24:695-701
Carnathan, Diane; Lawson, Benton; Yu, Joana et al. (2018) Reduced Chronic Lymphocyte Activation following Interferon Alpha Blockade during the Acute Phase of Simian Immunodeficiency Virus Infection in Rhesus Macaques. J Virol 92:
Adekambi, Toidi; Ibegbu, Chris C; Cagle, Stephanie et al. (2018) High Frequencies of Caspase-3 Expressing Mycobacterium tuberculosis-Specific CD4+ T Cells Are Associated With Active Tuberculosis. Front Immunol 9:1481
Ende, Zachary; Deymier, Martin J; Claiborne, Daniel T et al. (2018) HLA Class I Downregulation by HIV-1 Variants from Subtype C Transmission Pairs. J Virol :
Eckard, Allison Ross; O'Riordan, Mary Ann; Rosebush, Julia C et al. (2018) Vitamin D supplementation decreases immune activation and exhaustion in HIV-1-infected youth. Antivir Ther 23:315-324
Haddad, Lisa B; Wall, Kristin M; Kilembe, William et al. (2018) Bacterial vaginosis modifies the association between hormonal contraception and HIV acquisition. AIDS 32:595-604
Patel, Viraj V; Dange, Alpana; Rawat, Shruta et al. (2018) Barriers to HIV Testing Among Men Who Have Sex With Men in India Reached Online: Implications for Interventions. J Acquir Immune Defic Syndr 78:e30-e34

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