The broad, long-term objectives of the Biostatistics Core (Core F) are to provide a full spectrum of statistical consulting services for HIV/AIDS-related research ofthe UNC CFAR.
The specific aims i nclude (1) providing a full spectrum of collaborative biostatistical services, (2) serving as a liaison between AIDS researchers and statistical scientists within the UNC CFAR research community and beyond, (3) providing scientific leadership, (4) providing biostatistical training and education to the UNC CFAR research community, and (5) engaging in evaluation and strategic planning to address the changing needs ofthe UNC CFAR. To achieve these aims, members of Core F proactively engage UNC CFAR investigators to identify and deliver services essential for highly productive design, management, analysis and publication ofAIDS research. Core F contributes to the framing of hypotheses, development of study designs, preparation of grant applications, selection of best statistical strategies, and delivery of statistical analyses required for publications. Investigators new to AIDS research receive highest priority. Core F also serves as a nexus between statistical and biomedical scientists in HIV research. Through the Core, clinicians are linked to statistical coinvestigators, while statisticians initiating AIDS-related methods research are connected with clinical coinvestigators. Organization as a formal Biostatistics Cpre greatly enhances the efficiency and ability of the Core to connect communities of scientists and to provide mentoring and training in statistics to AIDS researchers. Strong institutional support from the Department of Biostatistics allows Core F to take full advantage of existing infrastructure, resources and contacts with faculty renowned for their expertise in specialized fields of statistics. The Core proactively seeks Biostatistics faculty and students interested in participating as new members of Core F.

Public Health Relevance

Consistent with the mission ofthe NIH CFAR Program, the Biostatistics Core delivers essential biostatistical support and expertise to HIV/AIDS investigators ofthe UNC CFAR. These collaborative contributions ensure investigators make measurements, inferences, and predictions that are accurate, precise, and relevant to their particular research goals.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI050410-16
Application #
8531839
Study Section
Special Emphasis Panel (ZAI1-ELB-A)
Project Start
2013-08-01
Project End
2016-07-31
Budget Start
2013-08-01
Budget End
2014-07-31
Support Year
16
Fiscal Year
2013
Total Cost
$443,383
Indirect Cost
$123,213
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Zhang, Alice; Pan, Xin; Wu, Feng et al. (2018) What Would an HIV Cure Mean to You? Qualitative Analysis from a Crowdsourcing Contest in Guangzhou, China. AIDS Res Hum Retroviruses 34:80-87
Ong, Jason J; Wu, Dan; Huang, Wenting et al. (2018) Pressured HIV testing ""in the name of love"": a mixed methods analysis of pressured HIV testing among men who have sex with men in China. J Int AIDS Soc 21:e25098
Tucker, Joseph D; Zhang, Alice; Zhao, Yang (2018) HIV Cure Research Crowdsourcing: An Author Response. AIDS Res Hum Retroviruses 34:2
Nwaohiri, Anuli N; Tang, Jennifer H; Stanczyk, Frank et al. (2018) Discordance between self-reported contraceptive use and detection of exogenous hormones among Malawian women enrolling in a randomized clinical trial. Contraception 97:354-356
Schauer, Amanda P; Sykes, Craig; Cottrell, Mackenzie L et al. (2018) Validation of an LC-MS/MS assay to simultaneously monitor the intracellular active metabolites of tenofovir, emtricitabine, and lamivudine in dried blood spots. J Pharm Biomed Anal 149:40-45
Elion, Richard A; Althoff, Keri N; Zhang, Jinbing et al. (2018) Recent Abacavir Use Increases Risk of Type 1 and Type 2 Myocardial Infarctions Among Adults With HIV. J Acquir Immune Defic Syndr 78:62-72
Mao, Jessica; Tang, Weiming; Liu, Chuncheng et al. (2018) Sex tourism among Chinese men who have sex with men: a cross-sectional observational study. BMC Public Health 18:306
Croffut, Samantha E; Hamela, Gloria; Mofolo, Innocent et al. (2018) HIV-positive Malawian women with young children prefer overweight body sizes and link underweight body size with inability to exclusively breastfeed. Matern Child Nutr 14:
Lancaster, Kathryn E; MacLean, Sarah A; Lungu, Thandie et al. (2018) Socioecological Factors Related to Hazardous Alcohol use among Female Sex Workers in Lilongwe, Malawi: A Mixed Methods Study. Subst Use Misuse 53:782-791
Sharma, Anjali; Hoover, Donald R; Shi, Qiuhu et al. (2018) Longitudinal study of falls among HIV-infected and uninfected women: the role of cognition. Antivir Ther 23:179-190

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