The goals of the Virology Core are to enhance the research capacity of the UNC CFAR research community by providing access to state-of-the-art tools for diagnosis and monitoring HIV+ patients in clinical trials, and providing leadership to promote HIV/AIDS research in this area through collaboration, training, and mentoring.
The specific aims are to 1) provide quality viral assays and services, 2) provide training and mentorship to the domestic and international CFAR community and build capacity at international sites, 3) provide leadership through activities locally, nationally, and internationally, 4) support NIH networks and CFAR-CFAR collaborations by participating in CHAVI, HPTN, IMPAACT, and ACTG, 5) support new CFAR initiatives through collaborations with UNC CFAR members, and 6) engage in evaluation and strategic planning, using input from user surveys, an Internal Advisory Board, and the CFAR External Advisory Board. Through these activities, the Virology Core will continue to provide key infrastructure support for the HIV/AIDS research activity of the CFAR membership. These activities will have a significant impact on the future of the epidemic by providing HIV, HCV, and HPV viral assays, including ultra-low copy number and POC assays, training and mentoring new US and international scientists, and providing leadership locally, nationally, and globally.
|Sin, Sang-Hoon; Kang, Sun Ah; Kim, Yongbaek et al. (2016) Kaposi's Sarcoma-Associated Herpesvirus Latency Locus Compensates for Interleukin-6 in Initial B Cell Activation. J Virol 90:2150-4|
|Rutstein, S E; Golin, C E; Wheeler, S B et al. (2016) On the front line of HIV virological monitoring: barriers and facilitators from a provider perspective in resource-limited settings. AIDS Care 28:1-10|
|Cottrell, Mackenzie L; Yang, Kuo H; Prince, Heather M A et al. (2016) A Translational Pharmacology Approach to Predicting Outcomes of Preexposure Prophylaxis Against HIV in Men and Women Using Tenofovir Disoproxil Fumarate With or Without Emtricitabine. J Infect Dis 214:55-64|
|Davis, Alissa; Meyerson, Beth E; Aghaulor, Blessing et al. (2016) Barriers to health service access among female migrant Ugandan sex workers in Guangzhou, China. Int J Equity Health 15:170|
|Chen, J; Malone, S; Prince, H M A et al. (2016) Model-Based Analysis of Unbound Lopinavir Pharmacokinetics in HIV-Infected Pregnant Women Supports Standard Dosing in the Third Trimester. CPT Pharmacometrics Syst Pharmacol 5:147-57|
|Davis, Nicole L; Miller, William C; Hudgens, Michael G et al. (2016) Maternal and Breastmilk Viral Load: Impacts of Adherence on Peripartum HIV Infections Averted-The Breastfeeding, Antiretrovirals, and Nutrition Study. J Acquir Immune Defic Syndr 73:572-580|
|Lancaster, Kathryn E; Go, Vivian F; Lungu, Thandie et al. (2016) Substance use and HIV infection awareness among HIV-infected female sex workers in Lilongwe, Malawi. Int J Drug Policy 30:124-31|
|O'Donnell, Julie K; Gaynes, Bradley N; Cole, Stephen R et al. (2016) Ongoing life stressors and suicidal ideation among HIV-infected adults with depression. J Affect Disord 190:322-8|
|Cottrell, Mackenzie L; Prince, Heather M A; Allmon, Andrew et al. (2016) Cervicovaginal and Rectal Fluid as a Surrogate Marker of Antiretroviral Tissue Concentration: Implications for Clinical Trial Design. J Acquir Immune Defic Syndr 72:498-506|
|Althoff, Keri N; Rebeiro, Peter F; Hanna, David B et al. (2016) A picture is worth a thousand words: maps of HIV indicators to inform research, programs, and policy from NA-ACCORD and CCASAnet clinical cohorts. J Int AIDS Soc 19:20707|
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