The Developmental Core is the largest component of the Miami CFAR and provides the major mechanism through which the CFAR can support innovative and collaborative research, particularly between basic and clinical investigators, assist in the mentoring and establishment of new/junior investigators and provide a path for students to participate in HIV/AIDS research. While the CFAR Developmental Core has a broad mission, its primary goal remains to support junior and unfunded investigators. Over the past 4 years, the Developmental Core of the DCFAR provided $1,241,772 in funding for 34 developmental awards that leveraged $17,500,745 dollars in extramural funding. The Miami CFAR Developmental Core will build upon the momentum established under DCFAR status and, with an expanded budget, is poised to broaden the type of science that it can support. Developmental awards will be made under 4 different categories, each with a unique mission. Applications will undergo rigorous peer review and will be prioritized on the basis of scientific merit, relevance to AIDS and ability to impact the research of a junior investigator. ? Awards for new/junior investigators that promote the career track of these junior scientists. ? Translational research awards that foster research between basic and clinical researchers. ? Awards on emerging concepts that comprise high risk but potentially high payoff research. ? Incentivizing awards that permit clinical fellows to conduct basic/translational research. The maintenance of junior/new researchers on a successful career path is a primary mission of the CFAR. As a consequence, the Developmental Core will maintain a rigorous mentorship program for minority and junior faculty and trainees interested in a career in basic, behavioral or clinical HIV/AIDS research. The mentoring program will provide guidance in grant writing, research methods and career development and will link junior investigators to an established research mentor. These activities lay the foundation for a strong future for AIDS research at UM and support for a new generation of investigators.

Public Health Relevance

The Core is a lifeline for many junior investigators that provides them with the resources to ready themselves for a competitive NIH grant application. The Developmental Core is currentley a mechanism at UM that provides mentoring for junior scientists and the presence of such a mentoring program is key to ensuring our young scientists are successful and become the next generation of AIDS investigators. Furthermore, the Developmental Core provides a mechanism to harness the tremendous research strengths at UM.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (ZAI1-RRS-A (J1))
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Miami School of Medicine
Coral Gables
United States
Zip Code
Cohen, Stephanie E; Vittinghoff, Eric; Bacon, Oliver et al. (2015) High interest in preexposure prophylaxis among men who have sex with men at risk for HIV infection: baseline data from the US PrEP demonstration project. J Acquir Immune Defic Syndr 68:439-48
Liu, Sicen; Dominska-Ngowe, Monika; Dykxhoorn, Derek Michael (2014) Target silencing of components of the conserved oligomeric Golgi complex impairs HIV-1 replication. Virus Res 192:92-102
András, Ibolya E; Toborek, Michal (2014) HIV-1 stimulates nuclear entry of amyloid beta via dynamin dependent EEA1 and TGF-?/Smad signaling. Exp Cell Res 323:66-76
Fekete, Erin M; Seay, Julia; Antoni, Michael H et al. (2014) Oxytocin, social support, and sleep quality in low-income minority women living with HIV. Behav Sleep Med 12:207-21
Thomas, Jaime M; Pos, Zoltan; Reinboth, Jennifer et al. (2014) Differential responses of plasmacytoid dendritic cells to influenza virus and distinct viral pathogens. J Virol 88:10758-66
Ashlock, Brittany M; Ma, Qi; Issac, Biju et al. (2014) Productively infected murine Kaposi's sarcoma-like tumors define new animal models for studying and targeting KSHV oncogenesis and replication. PLoS One 9:e87324
Weiss, Stephen M; Peltzer, Karl; Villar-Loubet, Olga et al. (2014) Improving PMTCT uptake in rural South Africa. J Int Assoc Provid AIDS Care 13:269-76
András, Ibolya E; Rampersaud, Evadnie; Eum, Sung Yong et al. (2014) Transcriptional profile of HIV-induced nuclear translocation of amyloid ? in brain endothelial cells. Arch Med Res 45:744-52
Mesri, Enrique A; Feitelson, Mark A; Munger, Karl (2014) Human viral oncogenesis: a cancer hallmarks analysis. Cell Host Microbe 15:266-82
Johnson, Daniel H; Venuto, Charles; Ritchie, Marylyn D et al. (2014) Genomewide association study of atazanavir pharmacokinetics and hyperbilirubinemia in AIDS Clinical Trials Group protocol A5202. Pharmacogenet Genomics 24:195-203

Showing the most recent 10 out of 59 publications