The Developmental Core (Core B) will support and develop the next-generation of HIV/AIDS researchers at the UR. The Core will administer the CFAR's pilot grant program, conduct mentoring and career development of young investigators, and provide seminars and scientific symposia that create an outstanding scientific and intellectual environment for HIV/AIDS research at the UR. The Core will use its pilot program to support young faculty and to also promote overall CFAR objectives, including the establishment of new multidisciplinary collaborations and the promotion of innovative studies that support the mission of the CFAR's Scientific Working Groups (SWGs) and leverage unique institutional assets. During our funding cycle as a Developmental CFAR (D-CFAR), this Core has funded 26 pilot awards in an aggregate amount of $641,606, which have yielded a 10:1 return on investment in terms of new grant awards. Its pilot and mentoring programs have also had a profound impact on the career development of young HIV/AIDS researchers. This has included 2 KL2 awards from the UR CTSI;2 awards from the national Creative New Ideas in HIV Research (CNIHR) program (out of only 22 total awards made between 2010 and 2012);4 CFAR supplement awards in 2011 (including 1 of only 2 nanotech supplements awarded nationally);and the academic promotion of 6 young faculty members.
Three Aims are proposed.
Aim 1 will stimulate new research on HIV/AIDS by funding pilot awards targeted to: young faculty members;innovative studies with potential for high impact;and multidisciplinary collaborations that span different departments and schools, including projects that leverage unique institutional assets.
Aim 2 will provide comprehensive, structured mentoring support for the early career development of young faculty, and a grant pre-review service intended to enhance the quality of extramural grant applications from new investigators. Finally, Aim 3 will create an outstanding intellectual and scientific environment for HIV/AIDS researchers, by supporting seminars, symposia, and a range of training courses and workshops.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Center Core Grants (P30)
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Special Emphasis Panel (ZAI1-UKS-A (J1))
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University of Rochester
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McMahon, James M; Pouget, Enrique R; Tortu, Stephanie et al. (2015) Couple-based HIV counseling and testing: a risk reduction intervention for US drug-involved women and their primary male partners. Prev Sci 16:341-51
McMahon, James M; Volpe, Ellen M; Klostermann, Keith et al. (2015) A systematic review of the psychometric properties of the Sexual Relationship Power Scale in HIV/AIDS research. Arch Sex Behav 44:267-94
Bobo, Bryan; Phelan, Dana; Rebhahn, Jonathan et al. (2014) Microbubble array diffusion assay for the detection of cell secreted factors. Lab Chip 14:3640-50
Liu, Zhi-Ping; Wu, Hulin; Zhu, Jian et al. (2014) Systematic identification of transcriptional and post-transcriptional regulations in human respiratory epithelial cells during influenza A virus infection. BMC Bioinformatics 15:336
Adler, David H; Wallace, Melissa; Bennie, Thola et al. (2014) Cervical dysplasia and high-risk human papillomavirus infections among HIV-infected and HIV-uninfected adolescent females in South Africa. Infect Dis Obstet Gynecol 2014:498048
Lewis, Cindi A; Dewhurst, Stephen; McMahon, James M et al. (2014) Theoretical model of critical issues in informed consent in HIV vaccine trials. AIDS Care 26:1452-60
McMahon, James M; Myers, Julie E; Kurth, Ann E et al. (2014) Oral pre-exposure prophylaxis (PrEP) for prevention of HIV in serodiscordant heterosexual couples in the United States: opportunities and challenges. AIDS Patient Care STDS 28:462-74
Piekna-Przybylska, Dorota; Sullivan, Mark A; Sharma, Gaurav et al. (2014) U3 region in the HIV-1 genome adopts a G-quadruplex structure in its RNA and DNA sequence. Biochemistry 53:2581-93
Morse, Diane S; Cerulli, Catherine; Bedell, Precious et al. (2014) Meeting health and psychological needs of women in drug treatment court. J Subst Abuse Treat 46:150-7
Silva, Jharon N; Polesskaya, Oksana; Wei, Helen S et al. (2014) Chronic central nervous system expression of HIV-1 Tat leads to accelerated rarefaction of neocortical capillaries and loss of red blood cell velocity heterogeneity. Microcirculation 21:664-76

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