The Biostatistics, Bioinformatics &Computational Biology Core (BBCB;Core E) will assist CFAR members with the management, analysis, modeling and annotation of complex and massive data generated by laboratory and clinical studies. The overall objective will be to provide a comprehensive solution that integrates expertise and resources in biostatistics, bioinformatics, computation, mathematical modeling and data management. Since its inception in 2010, Core E has developed and refined an innovative approach to optimally address investigator needs. This combines an integrated service model (

Public Health Relevance

The Biostatistics, Bioinformatics &Computational Biology Core (BBCB;Core E) will assist CFAR members with the management, analysis, modeling and annotation of complex and massive data generated by laboratory and clinical studies.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
2P30AI078498-06
Application #
8520715
Study Section
Special Emphasis Panel (ZAI1-UKS-A (J1))
Project Start
2008-05-01
Project End
2018-04-30
Budget Start
2013-05-01
Budget End
2014-04-30
Support Year
6
Fiscal Year
2013
Total Cost
$327,724
Indirect Cost
$99,679
Name
University of Rochester
Department
Type
DUNS #
041294109
City
Rochester
State
NY
Country
United States
Zip Code
14627
McMahon, James M; Pouget, Enrique R; Tortu, Stephanie et al. (2015) Couple-based HIV counseling and testing: a risk reduction intervention for US drug-involved women and their primary male partners. Prev Sci 16:341-51
McMahon, James M; Volpe, Ellen M; Klostermann, Keith et al. (2015) A systematic review of the psychometric properties of the Sexual Relationship Power Scale in HIV/AIDS research. Arch Sex Behav 44:267-94
Bobo, Bryan; Phelan, Dana; Rebhahn, Jonathan et al. (2014) Microbubble array diffusion assay for the detection of cell secreted factors. Lab Chip 14:3640-50
Liu, Zhi-Ping; Wu, Hulin; Zhu, Jian et al. (2014) Systematic identification of transcriptional and post-transcriptional regulations in human respiratory epithelial cells during influenza A virus infection. BMC Bioinformatics 15:336
Adler, David H; Wallace, Melissa; Bennie, Thola et al. (2014) Cervical dysplasia and high-risk human papillomavirus infections among HIV-infected and HIV-uninfected adolescent females in South Africa. Infect Dis Obstet Gynecol 2014:498048
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McMahon, James M; Myers, Julie E; Kurth, Ann E et al. (2014) Oral pre-exposure prophylaxis (PrEP) for prevention of HIV in serodiscordant heterosexual couples in the United States: opportunities and challenges. AIDS Patient Care STDS 28:462-74
Piekna-Przybylska, Dorota; Sullivan, Mark A; Sharma, Gaurav et al. (2014) U3 region in the HIV-1 genome adopts a G-quadruplex structure in its RNA and DNA sequence. Biochemistry 53:2581-93
Morse, Diane S; Cerulli, Catherine; Bedell, Precious et al. (2014) Meeting health and psychological needs of women in drug treatment court. J Subst Abuse Treat 46:150-7
Silva, Jharon N; Polesskaya, Oksana; Wei, Helen S et al. (2014) Chronic central nervous system expression of HIV-1 Tat leads to accelerated rarefaction of neocortical capillaries and loss of red blood cell velocity heterogeneity. Microcirculation 21:664-76

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