The Administrative Core will lead and govern the District of Columbia Developmental Center for AIDS Research (the """"""""DC D-CFAR"""""""") to address the overall mission and goals of the national CFAR Program, with a focus on the unique aspects ofthe DC D-CFAR - addressing the severe HIV/AIDS epidemic in Washington DC;developing HIV/AIDS research capacity among investigators, with a focus on junior and minority investigators, from the major academic institutions in the nation's capital;and capitalizing on the existing infrastructure and programs ofthe HIV/AIDS Institute.
The specific aims ofthe Administrative Core include the following: 1. Provide leadership and governance ofthe DC D-CFAR 2. Promote multidisciplinary and multi-institutional scientific HIV/AIDS research and educational activities 3. Ensure the responsible oversight and management of all DC D-CFAR fiscal and personnel resources 4. Ensure the continuous quality improvement of DC D-CFAR scientific and educational activities The Administrative Core will provide the leadership and infrastructure necessary for the Developmental and three Scientific Cores to function effectively in their promotion and delivery of research related to HIV/AIDS. Upon notification of funding, the Administrative Core would immediately facilitate the transition to a DC DCFAR. Throughout this transition the necessary steps would be taken to implement the fiscal mechanisms that will allow our multi-institutional D-CFAR to function;notify all Core Directors and Advisory Committee members about the award funding and the transition plan;and communicate with all members, potential Core users and other key stakeholders about the institution of the D-CFAR in Washington DC. Thereafter, the Administrative Core would continue to provide oversight and to manage the functioning ofthe DC D-CFAR through ongoing meetings, educational seminars, communication mechanisms, grant management, fiscal oversight and monitoring and evaluation activities that would allow for the continual growth of the DC D-CFAR as it builds the foundation necessary to function as a full CFAR in the future.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI087714-04
Application #
8492013
Study Section
Special Emphasis Panel (ZAI1-JBS-A)
Project Start
Project End
Budget Start
2013-06-01
Budget End
2014-05-31
Support Year
4
Fiscal Year
2013
Total Cost
$855,389
Indirect Cost
$233,522
Name
George Washington University
Department
Type
DUNS #
043990498
City
Washington
State
DC
Country
United States
Zip Code
20052
Xia, Jie; Reid, Terry-Elinor; Wu, Song et al. (2018) Maximal Unbiased Benchmarking Data Sets for Human Chemokine Receptors and Comparative Analysis. J Chem Inf Model 58:1104-1120
Xia, Jie; Hu, Huabin; Xue, Wenjie et al. (2018) The discovery of novel HDAC3 inhibitors via virtual screening and in vitro bioassay. J Enzyme Inhib Med Chem 33:525-535
PĂ©rez-Losada, Marcos; Arenas, Miguel; Castro-Nallar, Eduardo (2018) Microbial sequence typing in the genomic era. Infect Genet Evol 63:346-359
Leal, Fabio E; Menezes, Soraya Maria; Costa, Emanuela A S et al. (2018) Comprehensive Antiretroviral Restriction Factor Profiling Reveals the Evolutionary Imprint of the ex Vivo and in Vivo IFN-? Response in HTLV-1-Associated Neuroinflammation. Front Microbiol 9:985
Paquin-Proulx, D; Ching, C; Vujkovic-Cvijin, I et al. (2017) Bacteroides are associated with GALT iNKT cell function and reduction of microbial translocation in HIV-1 infection. Mucosal Immunol 10:69-78
Xia, Jie; Hsieh, Jui-Hua; Hu, Huabin et al. (2017) The Development of Target-Specific Pose Filter Ensembles To Boost Ligand Enrichment for Structure-Based Virtual Screening. J Chem Inf Model 57:1414-1425
Xia, Jie; Feng, Bo; Shao, Qianhang et al. (2017) Virtual Screening against Phosphoglycerate Kinase 1 in Quest of Novel Apoptosis Inhibitors. Molecules 22:
Levy, Matthew E; Phillips 2nd, Gregory; Magnus, Manya et al. (2017) A Longitudinal Analysis of Treatment Optimism and HIV Acquisition and Transmission Risk Behaviors Among Black Men Who Have Sex with Men in HPTN 061. AIDS Behav 21:2958-2972
Pollack, Ross A; Jones, R Brad; Pertea, Mihaela et al. (2017) Defective HIV-1 Proviruses Are Expressed and Can Be Recognized by Cytotoxic T Lymphocytes, which Shape the Proviral Landscape. Cell Host Microbe 21:494-506.e4
Avdoshina, Valeria; Caragher, Seamus P; Wenzel, Erin D et al. (2017) The viral protein gp120 decreases the acetylation of neuronal tubulin: potential mechanism of neurotoxicity. J Neurochem 141:606-613

Showing the most recent 10 out of 174 publications