The overarching goal ofthe Public Health and Policy (PHP) Core is to promote and increase innovative research on HIV/AIDS to stem the HIV/AIDS epidemic in the district and surrounding areas. This Core seeks to encourage relevant, applicable, public health, implementation and experimental research, with emphasis on multidisciplinary projects. The Core will bring together investigators with different areas of expertise and interest to promote scientific communication among researchers, community and policy makers as well as to facilitate collaboration among the disciplines, and between scientists and community. Moreover, it will take a leadership role in advancing research by providing methodological expertise to faculty at participating institutions in the D-CFAR, with particular attention given to the task of encouraging and mentoring junior investigators and those new to the field of HIV research.
Specific Aim 1 : To support the development and realization of high-quality multidisciplinary research projects by providing expertise to investigators on the conduct of research and by facilitating cross-disciplinary research collaboration.
Specific aim 2 : To contribute to the training and mentoring of new investigators, with emphasis on junior and minority investigators, to build and/or extend their work to disadvantaged communities, including ethnic/racial minorities, immigrant groups, low-income (poor) families, and sexual minorities.
Specific aim 3 : To contribute to the bridging ofthe scienceto- practice gap by strategically disseminating information on ongoing research and outcomes to the community, discussing the potential impact of the research at the community level and serving as a conduit to local, national and international policy makers..

Public Health Relevance

The Public Helath and Policy Core is a major contributor to the goals ofthe DC D-DFAR. It is closely connected to all the other cores. It will support high quality cross-disciplinary research on HIV/AIDS, contribute to the training of new investigators, and foster scientific/community/policy connections.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Center Core Grants (P30)
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Special Emphasis Panel (ZAI1-JBS-A)
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George Washington University
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Xia, Jie; Reid, Terry-Elinor; Wu, Song et al. (2018) Maximal Unbiased Benchmarking Data Sets for Human Chemokine Receptors and Comparative Analysis. J Chem Inf Model 58:1104-1120
Xia, Jie; Hu, Huabin; Xue, Wenjie et al. (2018) The discovery of novel HDAC3 inhibitors via virtual screening and in vitro bioassay. J Enzyme Inhib Med Chem 33:525-535
PĂ©rez-Losada, Marcos; Arenas, Miguel; Castro-Nallar, Eduardo (2018) Microbial sequence typing in the genomic era. Infect Genet Evol 63:346-359
Leal, Fabio E; Menezes, Soraya Maria; Costa, Emanuela A S et al. (2018) Comprehensive Antiretroviral Restriction Factor Profiling Reveals the Evolutionary Imprint of the ex Vivo and in Vivo IFN-? Response in HTLV-1-Associated Neuroinflammation. Front Microbiol 9:985
Paquin-Proulx, D; Ching, C; Vujkovic-Cvijin, I et al. (2017) Bacteroides are associated with GALT iNKT cell function and reduction of microbial translocation in HIV-1 infection. Mucosal Immunol 10:69-78
Xia, Jie; Hsieh, Jui-Hua; Hu, Huabin et al. (2017) The Development of Target-Specific Pose Filter Ensembles To Boost Ligand Enrichment for Structure-Based Virtual Screening. J Chem Inf Model 57:1414-1425
Xia, Jie; Feng, Bo; Shao, Qianhang et al. (2017) Virtual Screening against Phosphoglycerate Kinase 1 in Quest of Novel Apoptosis Inhibitors. Molecules 22:
Levy, Matthew E; Phillips 2nd, Gregory; Magnus, Manya et al. (2017) A Longitudinal Analysis of Treatment Optimism and HIV Acquisition and Transmission Risk Behaviors Among Black Men Who Have Sex with Men in HPTN 061. AIDS Behav 21:2958-2972
Pollack, Ross A; Jones, R Brad; Pertea, Mihaela et al. (2017) Defective HIV-1 Proviruses Are Expressed and Can Be Recognized by Cytotoxic T Lymphocytes, which Shape the Proviral Landscape. Cell Host Microbe 21:494-506.e4
Avdoshina, Valeria; Caragher, Seamus P; Wenzel, Erin D et al. (2017) The viral protein gp120 decreases the acetylation of neuronal tubulin: potential mechanism of neurotoxicity. J Neurochem 141:606-613

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