The overarching goal ofthe Public Health and Policy (PHP) Core is to promote and increase innovative research on HIV/AIDS to stem the HIV/AIDS epidemic in the district and surrounding areas. This Core seeks to encourage relevant, applicable, public health, implementation and experimental research, with emphasis on multidisciplinary projects. The Core will bring together investigators with different areas of expertise and interest to promote scientific communication among researchers, community and policy makers as well as to facilitate collaboration among the disciplines, and between scientists and community. Moreover, it will take a leadership role in advancing research by providing methodological expertise to faculty at participating institutions in the D-CFAR, with particular attention given to the task of encouraging and mentoring junior investigators and those new to the field of HIV research.
Specific Aim 1 : To support the development and realization of high-quality multidisciplinary research projects by providing expertise to investigators on the conduct of research and by facilitating cross-disciplinary research collaboration.
Specific aim 2 : To contribute to the training and mentoring of new investigators, with emphasis on junior and minority investigators, to build and/or extend their work to disadvantaged communities, including ethnic/racial minorities, immigrant groups, low-income (poor) families, and sexual minorities.
Specific aim 3 : To contribute to the bridging ofthe scienceto- practice gap by strategically disseminating information on ongoing research and outcomes to the community, discussing the potential impact of the research at the community level and serving as a conduit to local, national and international policy makers..

Public Health Relevance

The Public Helath and Policy Core is a major contributor to the goals ofthe DC D-DFAR. It is closely connected to all the other cores. It will support high quality cross-disciplinary research on HIV/AIDS, contribute to the training of new investigators, and foster scientific/community/policy connections.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Center Core Grants (P30)
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Special Emphasis Panel (ZAI1-JBS-A)
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George Washington University
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Lam, Sharon; Sung, Julia; Cruz, Conrad et al. (2015) Broadly-specific cytotoxic T cells targeting multiple HIV antigens are expanded from HIV+ patients: implications for immunotherapy. Mol Ther 23:387-95
Peterson, James; Cota, Michelle; Gray, Holly et al. (2015) Technology use in linking criminal justice reentrants to HIV care in the community: a qualitative formative research study. J Health Commun 20:245-51
Bukrinsky, Michael (2015) Extracellular cyclophilins in health and disease. Biochim Biophys Acta 1850:2087-95
Michaud, Henri-Alexandre; SenGupta, Devi; de Mulder, Miguel et al. (2014) Cutting edge: An antibody recognizing ancestral endogenous virus glycoproteins mediates antibody-dependent cellular cytotoxicity on HIV-1-infected cells. J Immunol 193:1544-8
Curtis, Kimberly; Rollins, Matthew; Carryl, Heather et al. (2014) Reduction of pyramidal and immature hippocampal neurons in pediatric simian immunodeficiency virus infection. Neuroreport 25:647-52
Eberhart, M G; Voytek, C D; Hillier, A et al. (2014) Travel distance to HIV medical care: a geographic analysis of weighted survey data from the Medical Monitoring Project in Philadelphia, PA. AIDS Behav 18:776-82
Mayer, Kenneth H; Wang, Lei; Koblin, Beryl et al. (2014) Concomitant socioeconomic, behavioral, and biological factors associated with the disproportionate HIV infection burden among Black men who have sex with men in 6 U.S. cities. PLoS One 9:e87298
Mannheimer, Sharon B; Wang, Lei; Wilton, Leo et al. (2014) Infrequent HIV testing and late HIV diagnosis are common among a cohort of black men who have sex with men in 6 US cities. J Acquir Immune Defic Syndr 67:438-45
Jennelle, Lucas; Hunegnaw, Ruth; Dubrovsky, Larisa et al. (2014) HIV-1 protein Nef inhibits activity of ATP-binding cassette transporter A1 by targeting endoplasmic reticulum chaperone calnexin. J Biol Chem 289:28870-84
Michaud, Henri-Alexandre; de Mulder, Miguel; SenGupta, Devi et al. (2014) Trans-activation, post-transcriptional maturation, and induction of antibodies to HERV-K (HML-2) envelope transmembrane protein in HIV-1 infection. Retrovirology 11:10

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