This is a revision of a new application to re-establish a Center for AIDS Research (CFAR) at the Johns Hopkins University (JHU). The new CFAR is comprised of more than 180 investigators from across all divisions of JHU and is based on a large portfolio of domestic and international HIV/AIDS research projects, with a Research Funding Base of $85 million for 165 grants to 136 Principal Investigators. This submission has been extensively revised on the basis of the critique of our 2010 application. We now propose six cores and three scientific working groups that will provide s a productive platform for promoting collaboration and synergy across the JHU HIV research community.
The aims ofthe JHU CFAR are to 1) Enhance integration and productivity of JHU HIV/AIDS research by promoting trans-disciplinary innovation and collaboration across disciplines and university divisions;2) Recruit new investigators into HIV/AIDS research to address the growing need for knowledge in rapidly emerging areas that affect the AIDS epidemic, e.g., co-infections, co-morbidities, substance abuse, and aging;3) Provide mentoring forth next generation of HIV/AIDS researchers and to recruit underrepresented minority investigators through mentoring and developmental grants;and 4) Mobilize the capacity of JHU to combat the HIV epidemic in Baltimore through engagement, training, outreach and community-based intervention studies.
These aims will be addressed across three broad themes: Development and Mentoring of New Investigators, Addressing the Baltimore HIV Epidemic, and Strengthening International Collaborations. We have garnered institutional commitments of $450,000 per year from the Provost and Deans of the medical, public health and nursing schools and $600,000 for leveraging recruitment of HIV investigators from Departments. This new CFAR represents a major commitment of investigators and institutional leadership to promote excellence, productivity and growth of HIV research and control efforts at JHU, in Baltimore and globally.

Public Health Relevance

HIV/AIDS is a major threat to global health and urban America. Research on HIV/AIDS has led to great improvements in the treatment and prevention of HIV disease, but much more needs to be done to control the epidemic. A CFAR will help coordinate, mobilize the substantial scientific, clinical and public health resources at JHU to generate new knowledge to understand, respond to, and control the HIV pandemic.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI094189-03
Application #
8653924
Study Section
Special Emphasis Panel (ZAI1-RRS-A (J1))
Program Officer
Namkung, Ann S
Project Start
2012-05-02
Project End
2017-04-30
Budget Start
2014-05-01
Budget End
2015-04-30
Support Year
3
Fiscal Year
2014
Total Cost
$2,999,995
Indirect Cost
$1,148,146
Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Edwards, Jessie K; Cole, Stephen R; Lesko, Catherine R et al. (2016) An Illustration of Inverse Probability Weighting to Estimate Policy-Relevant Causal Effects. Am J Epidemiol 184:336-44
Rebeiro, Peter F; Gange, Stephen J; Horberg, Michael A et al. (2016) Geographic Variations in Retention in Care among HIV-Infected Adults in the United States. PLoS One 11:e0146119
Solomon, Sunil Suhas; Mehta, Shruti H; McFall, Allison M et al. (2016) Community viral load, antiretroviral therapy coverage, and HIV incidence in India: a cross-sectional, comparative study. Lancet HIV 3:e183-90
Draughon Moret, Jessica E; Hauda 2nd, William E; Price, Bonnie et al. (2016) Nonoccupational Postexposure Human Immunodeficiency Virus Prophylaxis: Acceptance Following Sexual Assault. Nurs Res 65:47-54
Lucas, Gregory M; Atta, Mohamed G; Zook, Katie et al. (2016) Factors associated with iohexol-based glomerular filtration rate slope over 36 months in HIV-negative and HIV-positive individuals. AIDS 30:619-26
Saylor, Deanna; Dickens, Alex M; Sacktor, Ned et al. (2016) HIV-associated neurocognitive disorder--pathogenesis and prospects for treatment. Nat Rev Neurol 12:234-48
Farmer, Charles; Yehia, Baligh R; Fleishman, John A et al. (2016) Factors Associated With Retention Among Non-Perinatally HIV-Infected Youth in the HIV Research Network. J Pediatric Infect Dis Soc 5:39-46
Howe, Chanelle J; Cole, Stephen R; Lau, Bryan et al. (2016) Selection Bias Due to Loss to Follow Up in Cohort Studies. Epidemiology 27:91-7
Rainwater-Lovett, Kaitlin; Uprety, Priyanka; Persaud, Deborah (2016) Advances and hope for perinatal HIV remission and cure in children and adolescents. Curr Opin Pediatr 28:86-92
Haines, Charles F; Fleishman, John A; Yehia, Baligh R et al. (2016) Closing the Gap in Antiretroviral Initiation and Viral Suppression: Time Trends and Racial Disparities. J Acquir Immune Defic Syndr 73:340-347

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