The Sidney Kimmel Comprehensive Cancer Center (SKCCC) Cellular Therapy Core (CTC) consists of the clinical Cell Therapy Laboratory (CTL) in the Weinberg Building and the Process Optimization Laboratory (POL), a designated lab space in the Bunting-Blaustein Cancer Research Building for translational scale-up studies. This Core supports investigator sponsored clinical trials. These include technology transfer from the research laboratory to the clinical setting, scale up and validation studies. The staff within this laboratory has extensive experience in all aspects of cellular therapy including cGMP Phase l/ll manufacturing for autologous products, cGTP manufacturing of blood and bone marrow for transplantation, stem cell biology expertise, immunotherapy expertise and clinical experience in transplantation and cellular therapies. There is extensive QA/QC and regulatory experience for the development of products and compliance with FDA regulations. Staff in this Core also provide assistance in the preparation of regulatory documents including IND applications. Lay: The Cellular Therapy Core provides a critical service to cancer researchers by helping turn their promising laboratory findings into new cancer therapies that can treat patients. The Core staff work in a controlled laboratory with specialized equipment where they process and freeze blood-based stem cells for patients enrolled in clinical trials.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA006973-51
Application #
8661012
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2014-05-01
Budget End
2015-04-30
Support Year
51
Fiscal Year
2014
Total Cost
$225,956
Indirect Cost
$86,760
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
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