The Glassware Core and its 24 staff members employ over 100 pieces of equipment, throughout the Rockefeller, Schwartz and Zuckerman Research Centers, to deliver more than 5,000 pieces of cleaned and sterilized labware to more than 110 investigators and their staff. Daily routines include decontamination and collection of soiled labware;hand-scrubbing and visual inspection of each piece before further processing in commercial glasswashers;sorting, wrapping, and/or plugging followed by processing in high-temperature ovens and steam autoclaves before return to the laboratories. Specialized procedures also provide for acidwashing and RNase-free preparations. All processing follows standardized operating procedures specially adapted to meet the needs of each user, and is ascertained to meet the minimum standard of """"""""visually clean"""""""" or less than 4 ug/ml of debris, following the criteria for acceptance of LeBlanc and the FDA on the validation of cleaning processes. Over 90% of all work is restocked in each laboratory within an 8-hour time frame, providing cost and space savings to the laboratories. This core also provides dry ice stores throughout the research environment, assists with the monitoring of disposal of biohazardous waste and broken glass from laboratories, as well as provides for the decontamination of radioactive and other forms of biohazardous waste. To minimize costs to the laboratories, only """"""""hands-on"""""""" time is charged for all services. Changes are anticipated in operating procedures to allow increased standardization in washing with the use of acid and alkaline detergents in the glasswashing machines, further reducing the """"""""hands-on"""""""" time charged to users. When demand dictates, services will be expanded to include standardized cleaning of specialized laboratory equipment, such as cell and tissue incubators or freezers.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Center Core Grants (P30)
Project #
Application #
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Sloan-Kettering Institute for Cancer Research
New York
United States
Zip Code
Basaraba, Cale N; Westhoff, Carolyn L; Pike, Malcolm C et al. (2017) Estimating systemic exposure to levonorgestrel from an oral contraceptive. Contraception 95:398-404
Hernandez, Jonathan M; Beylergil, Volkan; Goldman, Debra A et al. (2017) Post-Treatment/Pre-operative PET Response Is Not an Independent Predictor of Outcomes for Patients With Gastric and GEJ Adenocarcinoma. Ann Surg :
Argani, Pedram; Kao, Yu-Chien; Zhang, Lei et al. (2017) Primary Renal Sarcomas With BCOR-CCNB3 Gene Fusion: A Report of 2 Cases Showing Histologic Overlap With Clear Cell Sarcoma of Kidney, Suggesting Further Link Between BCOR-related Sarcomas of the Kidney and Soft Tissues. Am J Surg Pathol 41:1702-1712
Moore, Kathleen N; Martin, Lainie P; O'Malley, David M et al. (2017) Safety and Activity of Mirvetuximab Soravtansine (IMGN853), a Folate Receptor Alpha-Targeting Antibody-Drug Conjugate, in Platinum-Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer: A Phase I Expansion Study. J Clin Oncol 35:1112-1118
Lee, Ser Yee; Goh, Brian K P; Sadot, Eran et al. (2017) Surgical Strategy and Outcomes in Duodenal Gastrointestinal Stromal Tumor. Ann Surg Oncol 24:202-210
Hyman, David M; Taylor, Barry S; Baselga, José (2017) Implementing Genome-Driven Oncology. Cell 168:584-599
Li, Gang G; Somwar, Romel; Joseph, James et al. (2017) Antitumor Activity of RXDX-105 in Multiple Cancer Types with RET Rearrangements or Mutations. Clin Cancer Res 23:2981-2990
Bhagat, Tushar D; Zou, Yiyu; Huang, Shizheng et al. (2017) Notch Pathway Is Activated via Genetic and Epigenetic Alterations and Is a Therapeutic Target in Clear Cell Renal Cancer. J Biol Chem 292:837-846
Prieto-Granada, Carlos N; Zhang, Lei; Antonescu, Cristina R et al. (2017) Primary cutaneous adenoid cystic carcinoma with MYB aberrations: report of three cases and comprehensive review of the literature. J Cutan Pathol 44:201-209
He, Mu; Agbu, Stephanie; Anderson, Kathryn V (2017) Microtubule Motors Drive Hedgehog Signaling in Primary Cilia. Trends Cell Biol 27:110-125

Showing the most recent 10 out of 7561 publications