The Bioinformatics Core (BIC) was created in early 2003 to build and provide bioinformatics services and infrastructure. The bioinformatics services and infrastructure provided to MSK investigators include scientific consultations, training, high performance computing and the development of institutional resources, and is provided by 6 fulltime staff members, lead by scientific director and assistant director, and guided by institutional leadership. Because the development of this infrastructure depends on the use of, and interoperability with existing external bioinformatics databases, software and standards, BIC has also spearheaded MSK involvement in the NCI caBIG initiative. Over the first several years of operation, BIC has become widely integrated into MSK investigator led basic, clinical and translational research. This integration is manifest by the breadth and depth of the usage of the services that its diverse group of bioinformatics professionals provides. Over the next five years, we expect the bioinformatics needs of the institution to grow gradually, but are mindful of the increased need for bioinformatics services and resources as the amount and complexity of biomedical data continues to grow - especially in light of NIH's The Cancer Genome Atlas initiative (TCGA).

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA008748-47
Application #
8375226
Study Section
Subcommittee G - Education (NCI)
Project Start
2012-01-09
Project End
2013-12-31
Budget Start
2012-01-09
Budget End
2012-12-31
Support Year
47
Fiscal Year
2012
Total Cost
$499,158
Indirect Cost
Name
Sloan-Kettering Institute for Cancer Research
Department
Type
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10065
Salo-Mullen, Erin E; Lynn, Patricio B; Wang, Lu et al. (2018) Contiguous gene deletion of chromosome 2p16.3-p21 as a cause of Lynch syndrome. Fam Cancer 17:71-77
Sigel, Carlie S; Krauss Silva, Vitor Werneck; Reid, Michelle D et al. (2018) Assessment of cytologic differentiation in high-grade pancreatic neuroendocrine neoplasms: A multi-institutional study. Cancer Cytopathol 126:44-53
Sauter, Craig S; Matasar, Matthew J; Schoder, Heiko et al. (2018) A phase 1 study of ibrutinib in combination with R-ICE in patients with relapsed or primary refractory DLBCL. Blood 131:1805-1808
Berry, Sean L; Tierney, Kevin P; Elguindi, Sharif et al. (2018) Five years' experience with a customized electronic checklist for radiation therapy planning quality assurance in a multicampus institution. Pract Radiat Oncol 8:279-286
Breitbart, William (2018) Jimmie C. Holland, M.D. Psychosomatics 59:123-124
Geller, Shamir; Pitter, Ken; Moskowitz, Alison et al. (2018) Treatment of Vulvar Mycosis Fungoides Tumors With Localized Radiotherapy. Clin Lymphoma Myeloma Leuk 18:e279-e281
Romesser, Paul B; Pei, Xin; Shi, Weiji et al. (2018) Prostate-Specific Antigen (PSA) Bounce After Dose-Escalated External Beam Radiation Therapy Is an Independent Predictor of PSA Recurrence, Metastasis, and Survival in Prostate Adenocarcinoma Patients. Int J Radiat Oncol Biol Phys 100:59-67
Ankerst, Donna P; Straubinger, Johanna; Selig, Katharina et al. (2018) A Contemporary Prostate Biopsy Risk Calculator Based on Multiple Heterogeneous Cohorts. Eur Urol 74:197-203
Scott, Jessica M; Nilsen, Tormod S; Gupta, Dipti et al. (2018) Exercise Therapy and Cardiovascular Toxicity in Cancer. Circulation 137:1176-1191
Routy, Bertrand; Le Chatelier, Emmanuelle; Derosa, Lisa et al. (2018) Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors. Science 359:91-97

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