DEVELOPMENTAL FUNDS. During the current grant period, MSKCC opened the first phase of the Zuckerman Research Center. This allowed additional space for MSKCC to expand its laboratory-based cancer research efforts. An effort to attract leading laboratory-based junior investigators was begun in 2006. The strategic planning for these recruitments was undertaken by the Senior Leadership and executed by search committees led by the Program Leaders with participation from the membership. To date, 17 junior investigators have been recruited and established independent laboratories in part supported by the CCSG funds. Over the last 6 years, a total of $4.7M in developmental funds were awarded to assist in establishing their laboratories. These funds have been instrumental in the success of these junior investigators at establishing successful independent laboratories. As a group they have received $38.1M in peer-reviewed funding (total award) and produced over 80 publications from their laboratories. All 8 of the laboratory-based research programs participated in and benefited from this influx of emerging talent. Many of the new investigators brought with them expertise in new areas or techniques of relevance to the evolving scope of cancer research. Funds are now being requested to support the mission of the Cancer Center in two categories critical to the advancement of its goals: 1) Additional faculty recruitment in disciplines related to the strategic vision of the Center and 2) Pilot project grants to stimulate cross-disciplinary collaboration between investigators in the Survivorship, Outcomes and Risk (SOAR) program and members of other Cancer Center programs. Both categories represent opportunities for the Center to strengthen and diversify its research portfolio. Funds requested to support faculty recruitment in strategic areas will enable the Center to attract top talent by providing a start-up/transition package that will enable new recruits to have the resources to immediately develop and grow their research programs. Funds requested to support cross-disciplinary pilot projects between SOAR and other Cancer Center program members will provide an opportunity for the development and initiation of research projects that build upon the expertise of the Center's population scientists, as well as exploit the knowledge of the Center's basic and clinical research community in order to facilitate the discovery of new knowledge.

Public Health Relevance

The recruitment of faculty in strategic areas, as well as the initiation of pilot projects bridging population sciences with other areas of investigation are critical elements to facilitating the discovery of new cancer-related knowledge.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA008748-50
Application #
8986751
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2016-01-01
Budget End
2016-12-31
Support Year
50
Fiscal Year
2016
Total Cost
$1,421,601
Indirect Cost
$621,601
Name
Sloan-Kettering Institute for Cancer Research
Department
Type
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10065
Steuer, Conor E; Behera, Madhusmita; Berry, Lynne et al. (2016) Role of race in oncogenic driver prevalence and outcomes in lung adenocarcinoma: Results from the Lung Cancer Mutation Consortium. Cancer 122:766-72
Dominguez-Rosado, Ismael; Moutinho Jr, Vitor; DeMatteo, Ronald P et al. (2016) Outcomes of the Memorial Sloan Kettering Cancer Center International General Surgical Oncology Fellowship. J Am Coll Surg 222:961-6
Iasonos, Alexia; O'Quigley, John (2016) Integrating the escalation and dose expansion studies into a unified Phase I clinical trial. Contemp Clin Trials 50:124-34
Ulaner, Gary A; Hyman, David M; Ross, Dara S et al. (2016) Detection of HER2-Positive Metastases in Patients with HER2-Negative Primary Breast Cancer Using 89Zr-Trastuzumab PET/CT. J Nucl Med 57:1523-1528
Brown, Anna M; Nagala, Sidhartha; McLean, Mary A et al. (2016) Multi-institutional validation of a novel textural analysis tool for preoperative stratification of suspected thyroid tumors on diffusion-weighted MRI. Magn Reson Med 75:1708-16
Akkari, Leila; Gocheva, Vasilena; Quick, Marsha L et al. (2016) Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer. Genes Dev 30:220-32
Theilen, Till M; Chou, Alexander J; Klimstra, David S et al. (2016) Esophageal Adenocarcinoma and Squamous Cell Carcinoma in Children and Adolescents: Report of 3 Cases and Comprehensive Literature Review. J Pediatr Surg Case Rep 5:23-29
Robinson, June K; Halpern, Allan C (2016) Cost-effective Melanoma Screening. JAMA Dermatol 152:19-21
Calzavara-Pinton, Pier Giacomo; Rossi, Maria Teresa; Zanca, Arianna et al. (2016) Oral Polypodium leucomotos increases the anti-inflammatory and melanogenic responses of the skin to different modalities of sun exposures: a pilot study. Photodermatol Photoimmunol Photomed 32:22-7
Ripley, R Taylor; Suzuki, Kei; Tan, Kay See et al. (2016) Postinduction positron emission tomography assessment of N2 nodes is not associated with ypN2 disease or overall survival in stage IIIA non-small cell lung cancer. J Thorac Cardiovasc Surg 151:969-77, 979.e1-3

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