DEVELOPMENTAL FUNDS. During the current grant period, MSKCC opened the first phase of the Zuckerman Research Center. This allowed additional space for MSKCC to expand its laboratory-based cancer research efforts. An effort to attract leading laboratory-based junior investigators was begun in 2006. The strategic planning for these recruitments was undertaken by the Senior Leadership and executed by search committees led by the Program Leaders with participation from the membership. To date, 17 junior investigators have been recruited and established independent laboratories in part supported by the CCSG funds. Over the last 6 years, a total of $4.7M in developmental funds were awarded to assist in establishing their laboratories. These funds have been instrumental in the success of these junior investigators at establishing successful independent laboratories. As a group they have received $38.1M in peer-reviewed funding (total award) and produced over 80 publications from their laboratories. All 8 of the laboratory-based research programs participated in and benefited from this influx of emerging talent. Many of the new investigators brought with them expertise in new areas or techniques of relevance to the evolving scope of cancer research. Funds are now being requested to support the mission of the Cancer Center in two categories critical to the advancement of its goals: 1) Additional faculty recruitment in disciplines related to the strategic vision of the Center and 2) Pilot project grants to stimulate cross-disciplinary collaboration between investigators in the Survivorship, Outcomes and Risk (SOAR) program and members of other Cancer Center programs. Both categories represent opportunities for the Center to strengthen and diversify its research portfolio. Funds requested to support faculty recruitment in strategic areas will enable the Center to attract top talent by providing a start-up/transition package that will enable new recruits to have the resources to immediately develop and grow their research programs. Funds requested to support cross-disciplinary pilot projects between SOAR and other Cancer Center program members will provide an opportunity for the development and initiation of research projects that build upon the expertise of the Center's population scientists, as well as exploit the knowledge of the Center's basic and clinical research community in order to facilitate the discovery of new knowledge.

Public Health Relevance

The recruitment of faculty in strategic areas, as well as the initiation of pilot projects bridging population sciences with other areas of investigation are critical elements to facilitating the discovery of new cancer-related knowledge.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA008748-52
Application #
9406238
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
Project End
Budget Start
2018-01-01
Budget End
2018-12-31
Support Year
52
Fiscal Year
2018
Total Cost
Indirect Cost
Name
Sloan-Kettering Institute for Cancer Research
Department
Type
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10065
Hicks, Angel Mier; DeRosa, Antonio; Raj, Micheal et al. (2018) Visceral Thromboses in Pancreas Adenocarcinoma: Systematic Review. Clin Colorectal Cancer 17:e207-e216
Phillips, Gregory S; Freites-Martinez, Azael; Hsu, Meier et al. (2018) Inflammatory dermatoses, infections, and drug eruptions are the most common skin conditions in hospitalized cancer patients. J Am Acad Dermatol 78:1102-1109
Chang, Matthew T; Penson, Alexander; Desai, Neil B et al. (2018) Small-Cell Carcinomas of the Bladder and Lung Are Characterized by a Convergent but Distinct Pathogenesis. Clin Cancer Res 24:1965-1973
Trevino, Kelly M; Litz, Brett; Papa, Anthony et al. (2018) Bereavement Challenges and Their Relationship to Physical and Psychological Adjustment to Loss. J Palliat Med 21:479-488
Hayes, Richard B; Ahn, Jiyoung; Fan, Xiaozhou et al. (2018) Association of Oral Microbiome With Risk for Incident Head and Neck Squamous Cell Cancer. JAMA Oncol 4:358-365
Chen, Nan; Li, Xiaoyu; Chintala, Navin K et al. (2018) Driving CARs on the uneven road of antigen heterogeneity in solid tumors. Curr Opin Immunol 51:103-110
Juric, Dejan; Rodon, Jordi; Tabernero, Josep et al. (2018) Phosphatidylinositol 3-Kinase ?-Selective Inhibition With Alpelisib (BYL719) in PIK3CA-Altered Solid Tumors: Results From the First-in-Human Study. J Clin Oncol 36:1291-1299
Kim, Kwanghee; Watson, Philip A; Lebdai, Souhil et al. (2018) Androgen Deprivation Therapy Potentiates the Efficacy of Vascular Targeted Photodynamic Therapy of Prostate Cancer Xenografts. Clin Cancer Res 24:2408-2416
McKay, Rana R; Montgomery, Bruce; Xie, Wanling et al. (2018) Post prostatectomy outcomes of patients with high-risk prostate cancer treated with neoadjuvant androgen blockade. Prostate Cancer Prostatic Dis 21:364-372
Kashan, Mahyar; Ghanaat, Mazyar; Hötker, Andreas M et al. (2018) Cystic Renal Cell Carcinoma: A Report on Outcomes of Surgery and Active Surveillance in Patients Retrospectively Identified on Pretreatment Imaging. J Urol 200:275-282

Showing the most recent 10 out of 8799 publications