The Developmental funds of the CCSG represent one vital component of the UAB-CCC Core grant by empowering the Center director to respond to and provide leadership for the scientific needs and priorities of the Center. The UAB CCC uses these funds in three primary ways. First, New Investigator funds are combined with other Center funds (e.g., gift account) and funds from departments and other Centers to provide attractive recruitment packages for faculty important to the Cancer Center's research enterprise. These recruitments may represent a build-up for a new research initiative, expansion of an existing program or replacement for departing or retiring faculty. The second use of these funds is for our Pilot Grant Program with an emphasis on young or new faculty and inter- and intra-programmatic collaborative research programs. The CCC fully funds 3 pilot grants annually ($30,000 each) and contributes to 3 others (Core grant - $10,000 and ACS Institutional Research Grant - $30,000) in 2 separate annual competitions. Our Scientific Advisory Committee reviews and critiques these applications for Cancer Center research priorities and potential for extramural funding. The recipients of these funds have an excellent track record of successful grant funding (more than $10 million in extramural direct costs) and adding to the scientific growth of our programs. Third, development funding is used to invest in new research technologies that the Center membership find of significant value yet cannot afford to implement individually. This investment manifests itself as expansion of the capabilities of a current shared facility or the creation of a new shared facility centered on the new technology. During the last funding cycle of the UAB-CCC there were fifteen new investigators supported by CCSG Development dollars, thirty-two junior investigators received pilot funding, 16 collaborative programmatic grants were awarded, including six focused on HIV-associated malignancies, one new developing shared facility was started, and another four received significant upgrades in technology. All the efforts of the CCSG Development dollars were implemented to further the mission of the Center and provide added value to the CCC membership.

Public Health Relevance

The Developmental budget provided by the CCSG allows the UAB CCC Director flexibility in targeting the funding to high priority needs of the Center. The funding is most often used in the areas of strategic faculty recruitment, funding innovative research projects, spurring collaborative research programs and investing in new technologies that will be made available to the membership through new or existing shared facilities.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA013148-41
Application #
8732227
Study Section
Subcommittee G - Education (NCI)
Project Start
1997-03-28
Project End
2016-03-31
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
41
Fiscal Year
2013
Total Cost
$527,211
Indirect Cost
$68,572
Name
University of Alabama Birmingham
Department
Type
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Carson, Tiffany L; Wang, Fuchenchu; Cui, Xiangqin et al. (2018) Associations Between Race, Perceived Psychological Stress, and the Gut Microbiota in a Sample of Generally Healthy Black and White Women: A Pilot Study on the Role of Race and Perceived Psychological Stress. Psychosom Med 80:640-648
Williams, Adele P; Waters, Alicia M; Stewart, Jerry E et al. (2018) A novel retinoid X receptor agonist, UAB30, inhibits rhabdomyosarcoma cells in vitro. J Surg Res 228:54-62
Frugé, Andrew D; Cases, Mallory G; Howell, Carrie R et al. (2018) Fingernail and toenail clippings as a non-invasive measure of chronic cortisol levels in adult cancer survivors. Cancer Causes Control 29:185-191
McCaw, Tyler R; Randall, Troy D; Arend, Rebecca C (2018) Overcoming immune suppression with epigenetic modification in ovarian cancer. Transl Res :
Geng, Mengxin; Austin, Frank; Shin, Ronald et al. (2018) Covalent Structure and Bioactivity of the Type AII Lantibiotic Salivaricin A2. Appl Environ Microbiol 84:
Samykutty, Abhilash; Grizzle, William E; Fouts, Benjamin L et al. (2018) Optoacoustic imaging identifies ovarian cancer using a microenvironment targeted theranostic wormhole mesoporous silica nanoparticle. Biomaterials 182:114-126
Friedman, Gregory K; Bernstock, Joshua D; Chen, Dongquan et al. (2018) Enhanced Sensitivity of Patient-Derived Pediatric High-Grade Brain Tumor Xenografts to Oncolytic HSV-1 Virotherapy Correlates with Nectin-1 Expression. Sci Rep 8:13930
Powell, T Clark; Dilley, Sarah E; Bae, Sejong et al. (2018) The Impact of Racial, Geographic, and Socioeconomic Risk Factors on the Development of Advanced-Stage Cervical Cancer. J Low Genit Tract Dis 22:269-273
Kasten, Benjamin B; Oliver, Patsy G; Kim, Harrison et al. (2018) 212Pb-Labeled Antibody 225.28 Targeted to Chondroitin Sulfate Proteoglycan 4 for Triple-Negative Breast Cancer Therapy in Mouse Models. Int J Mol Sci 19:
Subramaniam, Akila; Blanchard, Christina T; Erickson, Britt K et al. (2018) Feasibility of Complete Salpingectomy Compared With Standard Postpartum Tubal Ligation at Cesarean Delivery: A Randomized Controlled Trial. Obstet Gynecol 132:20-27

Showing the most recent 10 out of 747 publications