Several pilot project RFAs were offered over this funding period to specifically address AECC goals identified within the context of the Center's strategic planning mechanism and the yearly meetings of the External Scientific Advisory Committee, (i) The first pilot project RFA issued in 2008 was focused on stimulating collaborations between clinical and laboratory investigators with the objective of promoting translational research within the context of a clinical study. A requirement was that the investigator participated in a disease-oriented focus group at the AECC Advances retreat, (ii) The second pilot project RFA was issued in Spring 2010. This initiative grew out of the Breast Cancer Working Group's activities and need to strengthen translational research in breast cancer with the context of the Tumor Microenvironment and Metastasis program. The RFA requested a range of proposals that address tumor and/or host factors contributing to metastasis, predictive markers of metastases, etc. (iii) The third RFA (January 2011) provided grants to support utilization of AECC Shared Resources in order to obtain preliminary data to support a grant application. Total awards in support of all pilot projects through the CCSG mechanism was $350,000. Representative projects supported by the CCSG are described here.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Center Core Grants (P30)
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Subcommittee G - Education (NCI)
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Albert Einstein College of Medicine
United States
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Peregrina, Karina; Houston, Michele; Daroqui, Cecilia et al. (2015) Vitamin D is a determinant of mouse intestinal Lgr5 stem cell functions. Carcinogenesis 36:25-31
Kim, Ryung S (2015) A new comparison of nested case-control and case-cohort designs and methods. Eur J Epidemiol 30:197-207
Arora, Pooja; Baena, Andres; Yu, Karl O A et al. (2014) A single subset of dendritic cells controls the cytokine bias of natural killer T cell responses to diverse glycolipid antigens. Immunity 40:105-16
Stanley, Pamela (2014) Galectin-1 Pulls the Strings on VEGFR2. Cell 156:625-6
Yamane, Fumihiro; Nishikawa, Yumiko; Matsui, Kazue et al. (2014) CSF-1 receptor-mediated differentiation of a new type of monocytic cell with B cell-stimulating activity: its selective dependence on IL-34. J Leukoc Biol 95:19-31
Singh, M; Quispe-Tintaya, W; Chandra, D et al. (2014) Direct incorporation of the NKT-cell activator ?-galactosylceramide into a recombinant Listeria monocytogenes improves breast cancer vaccine efficacy. Br J Cancer 111:1945-54
Bahde, Ralf; Kapoor, Sorabh; Viswanathan, Preeti et al. (2014) Endothelin-1 receptor A blocker darusentan decreases hepatic changes and improves liver repopulation after cell transplantation in rats. Hepatology 59:1107-17
Ho, Gloria Y F; Wang, Tao; Zheng, Siqun L et al. (2014) Circulating soluble cytokine receptors and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev 23:179-88
Ghartey, Jeny P; Smith, Benjamin C; Chen, Zigui et al. (2014) Lactobacillus crispatus dominant vaginal microbiome is associated with inhibitory activity of female genital tract secretions against Escherichia coli. PLoS One 9:e96659
Kerns, Sarah L; de Ruysscher, Dirk; Andreassen, Christian N et al. (2014) STROGAR - STrengthening the Reporting Of Genetic Association studies in Radiogenomics. Radiother Oncol 110:182-8

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