The Functional Genomics Facility provides cDNA microarrays, Affymetrix oligo arrays, and computational and experimental support for investigators conducting studies of gene expression. The Facility also provides gene expression analysis using real time PCR. The real time PCR service is helpful to investigators conducting studies of gene expression profiling, copy number determination of DNA or RNA targets, siRNA knockdown validation, allelic discrimination/SNP genotyping, transgenic mouse genotyping, biodistribution studies of gene therapy products, and microbial detection.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA014195-38
Application #
8208701
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2010-12-01
Budget End
2011-11-30
Support Year
38
Fiscal Year
2011
Total Cost
$195,391
Indirect Cost
Name
Salk Institute for Biological Studies
Department
Type
DUNS #
078731668
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Evan, Gerard I; Hah, Nasun; Littlewood, Trevor D et al. (2017) Re-engineering the Pancreas Tumor Microenvironment: A ""Regenerative Program"" Hacked. Clin Cancer Res 23:1647-1655
Liu, Hao; Naxerova, Kamila; Pinter, Matthias et al. (2017) Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreatic Ductal Adenocarcinoma. Clin Cancer Res 23:5959-5969
Gasser, Emanuel; Moutos, Christopher P; Downes, Michael et al. (2017) FGF1 - a new weapon to control type 2 diabetes mellitus. Nat Rev Endocrinol 13:599-609
Chen, Peiwen; Zuo, Hao; Xiong, Hu et al. (2017) Gpr132 sensing of lactate mediates tumor-macrophage interplay to promote breast cancer metastasis. Proc Natl Acad Sci U S A 114:580-585
Manoogian, Emily N C; Panda, Satchidananda (2017) Circadian rhythms, time-restricted feeding, and healthy aging. Ageing Res Rev 39:59-67
Fan, Weiwei; Waizenegger, Wanda; Lin, Chun Shi et al. (2017) PPAR? Promotes Running Endurance by Preserving Glucose. Cell Metab 25:1186-1193.e4
Tufail, Yusuf; Cook, Daniela; Fourgeaud, Lawrence et al. (2017) Phosphatidylserine Exposure Controls Viral Innate Immune Responses by Microglia. Neuron 93:574-586.e8
Li, Dongming; Palanca, Ana Marie S; Won, So Youn et al. (2017) The MBD7 complex promotes expression of methylated transgenes without significantly altering their methylation status. Elife 6:
Wu, Min-Zu; Cheng, Wei-Chung; Chen, Su-Feng et al. (2017) miR-25/93 mediates hypoxia-induced immunosuppression by repressing cGAS. Nat Cell Biol 19:1286-1296
Doktorova, Marcela; Zwarts, Irene; Zutphen, Tim van et al. (2017) Intestinal PPAR? protects against diet-induced obesity, insulin resistance and dyslipidemia. Sci Rep 7:846

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