The Integrative Genomics and Bioinformatics Core (IGC) specializes in the analysis of next-generation sequencing and other high-throughput genomics data. The IGC was established to assist the Salk community with the integration of genomics data into their research. The primary focus of the core is to provide analysis support for next-generation sequencing applications. The IGC offers a variety of services to suit the needs of different research groups, but is also committed to providing customized assistance to maintain the highest levels of scientific achievement for Salk researchers. All CCSG supported core are organized into one group: Basic Research. This shared resource is catagorized as category (7.02) Bioinformatics in summary 1D

Public Health Relevance

Data about cell function, particularly genomics data, is expanding dramatically. This resource will provide Cancer Center investigators with access to state-of-the-art bioinformatics and genomics analysis.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA014195-41
Application #
8934272
Study Section
Subcommittee G - Education (NCI)
Program Officer
Ciolino, Henry P
Project Start
2013-12-01
Project End
2018-11-30
Budget Start
2013-12-01
Budget End
2014-11-30
Support Year
41
Fiscal Year
2014
Total Cost
$354,155
Indirect Cost
$172,845
Name
Salk Institute for Biological Studies
Department
Type
DUNS #
078731668
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Lew, Erin D; Oh, Jennifer; Burrola, Patrick G et al. (2014) Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities. Elife 3:
Aslanian, Aaron; Yates 3rd, John R; Hunter, Tony (2014) Mass spectrometry-based quantification of the cellular response to methyl methanesulfonate treatment in human cells. DNA Repair (Amst) 15:29-38
Xia, Yifeng; Shen, Shen; Verma, Inder M (2014) NF-?B, an active player in human cancers. Cancer Immunol Res 2:823-30
Chaix, Amandine; Zarrinpar, Amir; Miu, Phuong et al. (2014) Time-restricted feeding is a preventative and therapeutic intervention against diverse nutritional challenges. Cell Metab 20:991-1005
Evans, Ronald M; Mangelsdorf, David J (2014) Nuclear Receptors, RXR, and the Big Bang. Cell 157:255-66
Islam, Md Soriful; Catherino, William H; Protic, Olga et al. (2014) Role of activin-A and myostatin and their signaling pathway in human myometrial and leiomyoma cell function. J Clin Endocrinol Metab 99:E775-85
Buchwalter, Abigail L; Liang, Yun; Hetzer, Martin W (2014) Nup50 is required for cell differentiation and exhibits transcription-dependent dynamics. Mol Biol Cell 25:2472-84
Liu, Guang-Hui; Suzuki, Keiichiro; Li, Mo et al. (2014) Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs. Nat Commun 5:4330
Korf, Katharina; Wodrich, Harald; Haschke, Alexander et al. (2014) The PML domain of PML-RAR? blocks senescence to promote leukemia. Proc Natl Acad Sci U S A 111:12133-8
Hatori, Megumi; Gill, Shubhroz; Mure, Ludovic S et al. (2014) Lhx1 maintains synchrony among circadian oscillator neurons of the SCN. Elife 3:e03357

Showing the most recent 10 out of 105 publications