The primary goal of the Cancer Informatics Shared Resource (CISR) is to provide UW Carbone Cancer Center (UWCCC) members with access to technologies, services and scientific consultation to aid in their mission to prevent, diagnose and treat cancer. The CISR works to provide members with modern and efficient informatics, including advancements in bioinformatics, clinical informatics, image analysis and computational science in a cost-effective manner. To accomplish this, the CISR offers technological resources and services to members including an informatics infrastructure for collecting, storing, analyzing and sharing of data;support for systems integration;and the development of specialized tools and/or the implementation of third-party tools. In addition, the CISR offers intellectual resources and services by providing members access to a wide range of skills and expertise in biomedical informatics to improve data collection, interpreting research data sets using existing analysis methods and technologies and developing new methodology when needed. The need for biomedical informatics in cancer research has only increased in the period since our last renewal. Therefore, UWCCC is working to develop a more robust cancer-managed informatics infrastructure and partnering with the UW-Madison CTSA-funded Institute for Clinical and Translational Research to significantly improve its capacity to develop the complex, and costly, services and resources that benefit biomedical research. New opportunities for this collaboration include the unification of UWCCC and ICTR Clinical Research Management System, integration with the UW Health Electronic Medical Record and interface with the UW Data Warehouse.
The goal of the Cancer Informatics Shared Resource (CISR) is to help UWCCC researchers in their mission to prevent, diagnose and treat cancer. The success of cancer research has become increasingly dependent on the analysis of large amounts of research data. To this end, the CISR provides researchers with the tools, expertise and technical resources to manage data in an efficient and cost-effective manner to further their research objectives.
|Oberley, Christopher C; Bilger, Andrea; Drinkwater, Norman R (2015) Genetic background determines if Stat5b suppresses or enhances murine hepatocarcinogenesis. Mol Carcinog 54:959-70|
|Wisinski, Kari B; Ledesma, Wendy M; Kolesar, Jill et al. (2015) A phase I study to determine the maximum tolerated dose and safety of oral LR-103 (1?,24(S)Dihydroxyvitamin D2) in patients with advanced cancer. J Oncol Pharm Pract 21:416-24|
|Kolesar, Jill M; Pomplun, Marcia; Havighurst, Tom et al. (2015) Soy food frequency questionnaire does not correlate with baseline isoflavone levels in patients with bladder cancer. J Oncol Pharm Pract 21:128-31|
|Simoncic, Urban; Perlman, Scott; Liu, Glenn et al. (2015) Comparison of NaF and FDG PET/CT for assessment of treatment response in castration-resistant prostate cancers with osseous metastases. Clin Genitourin Cancer 13:e7-e17|
|Zhao, Z; Wang, L; Xu, W (2015) IL-13R?2 mediates PNR-induced migration and metastasis in ER?-negative breast cancer. Oncogene 34:1596-607|
|Chakravarty, Rubel; Hong, Hao; Cai, Weibo (2015) Image-Guided Drug Delivery with Single-Photon Emission Computed Tomography: A Review of Literature. Curr Drug Targets 16:592-609|
|Wu, Jianqiang; Salva, Katrin A; Wood, Gary S (2015) c-CBL E3 ubiquitin ligase is overexpressed in cutaneous T-cell lymphoma: its inhibition promotes activation-induced cell death. J Invest Dermatol 135:861-8|
|LoConte, Noelle K; Razak, Albiruni R A; Ivy, Percy et al. (2015) A multicenter phase 1 study of ? -secretase inhibitor RO4929097 in combination with capecitabine in refractory solid tumors. Invest New Drugs 33:169-76|
|Romens, Sarah E; McDonald, Jennifer; Svaren, John et al. (2015) Associations between early life stress and gene methylation in children. Child Dev 86:303-9|
|Ayvaci, Mehmet U S; Alagoz, Oguzhan; Chhatwal, Jagpreet et al. (2014) Predicting invasive breast cancer versus DCIS in different age groups. BMC Cancer 14:584|
Showing the most recent 10 out of 472 publications