The Biostatistics Core Facility (BCF) of the University of Chicago Comprehensive Cancer Center (UCCCC) provides collaborative statistical support to UCCCC investigators engaged in clinical, basic, and population science research. The Facility is currently staffed by five PhD statisticians, two masters level biostatisticians, and one research programmer in addition to the Scientific and Technical Directors. The services provided by the BCF include collaboration in the formation of study designs and data analysis plans;protocol development, randomization, and statistical analysis for Phase 1, Phase 11, and Phase 111 clinical trials;assistance in the design and analysis of retrospective and prospective observational studies;and statistical collaboration on basic science and animal research projects. Clarification of specific aims and hypotheses to be tested, specification of primary and secondary outcome variables, sample-size (power) calculations, and development of data analysis plans are major areas of activity during the study design phase, followed by statistical analysis and assistance in the preparation of manuscripts for publication after completion of data collection. The BCF also interacts closely with the Cancer Clinical Trials Office and the UCCCC IT group on database development and data management procedures to ensure a high level of data quality for clinical trials and other studies conducted within the UCCCC, as well as the newly developing Bioinformatics Core to support investigators engaged in bioinformatics research and other

Public Health Relevance

The BCF plays a major role in assisting the UCCCC to meet its scientific objectives by ensuring that studies are efficiently designed, and that the data arising from those studies are appropriately analyzed and interpreted. Biostatisticians in the BCF provide essential services to Cancer Center investigators by collaborating on the design and execution of pilot studies and in the development of new grant proposals, as well as providing statistical analysis support for ongoing studies and funded research.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
2P30CA014599-38
Application #
8486648
Study Section
Subcommittee G - Education (NCI)
Project Start
2013-04-01
Project End
2018-03-31
Budget Start
2013-04-23
Budget End
2014-03-31
Support Year
38
Fiscal Year
2013
Total Cost
$197,235
Indirect Cost
Name
University of Chicago
Department
Type
DUNS #
005421136
City
Chicago
State
IL
Country
United States
Zip Code
60637
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